Etravirine Iimpurity 8 CAS CATO-C4X-13568
| CAS No. | CATO-C4X-13568 |
| Molecular Formula | C20H14BrN7O2 |
| Molecular Weight | 464.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Etravirine Iimpurity 8 (CAS CATO-C4X-13568, C20H14BrN7O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Etravirine Iimpurity 8 (C20H14BrN7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Etravirine Iimpurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H14BrN7O2 |
| Molecular Weight | 464.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 7 |
Related Etravirine Standards
Recommended Standards
- N-[(1E)-{[(2,6-dichlorophenyl)methoxy]imino}methyl]-2-(4-fluorophenoxy)-4-methoxypyridine-3-carboxamide (CAS 341966-65-2)
- 2-(4-Bromophenyl)-6-methyl-1-[4-(trifluoromethoxy)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one (CAS 1024400-40-5)
- N-[(1E)-{[(2,4-dichlorophenyl)methoxy]imino}methyl]-2-(4-fluorophenoxy)-4-methoxypyridine-3-carboxamide (CAS 341966-68-5)
- 2-[3-(2-Chloro-6-fluorophenyl)-4-methyl-1,2-oxazol-5-yl]-7-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (CAS 860611-27-4)
- Fexofenadine EP Impurity F (CAS 185066-33-5)
- Iomeprol Impurity 4 (CAS 2068038-50-4)
- Bromhexine EP Impurity D (CAS 132004-28-5)
- 2-[(E)-[(4-Phenoxyphenyl)methylidene]amino]-5-phenylfuran-3-carbonitrile (CAS 478033-33-9)
- 1,1-Dimethylethyl N-[(4-bromo-2-chloro-5-fluorophenyl)methyl]carbamate (CAS 1798842-32-6)
- N-((1-(2-Aminoethyl)piperidin-2-yl)methyl)-N-ethylacetamide (CAS 1353965-33-9)
- (4Z)-4-[(1H-Indol-3-yl)methylidene]-1,3-diphenyl-4,5-dihydro-1H-pyrazol-5-one (CAS 884259-09-0)
- 2-(Difluoromethyl)-3-iodo-4-(trifluoromethyl)pyridine-6-acetonitrile (CAS 1805198-32-6)
- 1-(3-Chloropropyl)-3,4-dihydroquinolin-2(1H)-one (CAS 79145-37-2)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com