4-Chloro-2-methylbenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate CAS 1144035-27-7
| CAS No. | 1144035-27-7 |
| Molecular Formula | C23H24ClN3O5 |
| Molecular Weight | 457.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-2-methylbenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Chloro-2-methylbenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-27-7), a certified reference material (molecular formula C23H24ClN3O5, MW 457.91 g/mol) for analytical method development and quality control.
4-Chloro-2-methylbenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (C23H24ClN3O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H24ClN3O5 |
| Molecular Weight | 457.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-Chloro-N-((2S,3R)-4-((3R,4S)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide (CAS 186392-65-4)
- 2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbonyl)-N-phenylhydrazine-1-carbothioamide (CAS 321430-55-1)
- N-(2-Chloro-4-fluorophenyl)-2-{[3-cyano-4-(trifluoromethyl)-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-2-yl]sulfanyl}acetamide (CAS 626227-45-0)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl 4-methoxybenzene-1-sulfonate (CAS 338402-41-8)
- 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol (CAS 142569-70-8)
- 2-[(2E)-2-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-ylidene}ethyl]-9,10-dihydroanthracene-9,10-dione (CAS 338961-95-8)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[2-(2-nitroethyl)phenyl]piperazine-1-carboxamide (CAS 339110-84-8)
- N-(5-chloro-2-methoxyphenyl)-2-(3,4-dichlorophenyl)quinoline-4-carboxamide (CAS 332176-51-9)
Recommended Standards
- Dacomitinib Impurity 10 (CAS CATO-C4X-208610)
- 4-Chlorobenzyl 4-(3-(5-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)-3-oxopropyl)piperazine-1-carboxylate (CAS 1144035-43-7)
- (E)-[(4-{[(4-chlorophenyl)methyl]sulfanyl}-3-nitrophenyl)methylidene][(4-nitrophenyl)methoxy]amine (CAS 303996-27-2)
- Tris(2,2,3,3,3-pentafluoropropyl) borate (CAS 2003-04-5)
- Ethyl 1H-Pyrazolo[3,4-d]pyrimidine-6-carboxylate (CAS 2106690-78-0)
- Ethyl 2-methoxyethanimidoate hydrochloride (CAS 42945-65-3)
- (R,S)-[1-(Benzyloxy)-2-oxo-3-azetidinyl]carbamic Acid Benzyl Ester (CAS 1246814-58-3)
- 4,7-Dichloro-8-fluoro-6-(trifluoromethyl)quinazoline (CAS 1698027-66-5)
- 2'-Chloroacetoacetanilide (CAS 93-70-9)
- 4-(6-{[(4-chlorophenyl)sulfanyl]methyl}-2-{[(4-fluorophenyl)methyl]sulfanyl}pyrimidin-4-yl)morpholine (CAS 341965-47-7)
- 3-Hydroxy-N-methoxy-N-methylcyclobutane-1-carboxamide (CAS 1187595-64-7)
- 1-(1,4-Dioxaspiro[4.5]Decan-8-yl)-1H-pyrazol-4-amine (CAS 2433769-82-3)
- (E)-Methyl 5-methylhex-2-enoate (CAS 75513-56-3)
- Cycloaspeptide D (CAS 691363-62-9)
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