5-Chloro-N-((2S,3R)-4-((3R,4S)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide CAS 186392-65-4
| CAS No. | 186392-65-4 |
| Molecular Formula | C23H24ClN3O5 |
| Molecular Weight | 457.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Chloro-N-((2S,3R)-4-((3R,4S)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide (CAS 186392-65-4), a certified reference material (molecular formula C23H24ClN3O5, MW 457.91 g/mol) for analytical method development and quality control.
Based on its molecular formula C23H24ClN3O5, 5-Chloro-N-((2S,3R)-4-((3R,4S)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 457.91 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H24ClN3O5 |
| Molecular Weight | 457.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2010 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-2-methylbenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144035-27-7)
- 2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbonyl)-N-phenylhydrazine-1-carbothioamide (CAS 321430-55-1)
- N-(2-Chloro-4-fluorophenyl)-2-{[3-cyano-4-(trifluoromethyl)-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-2-yl]sulfanyl}acetamide (CAS 626227-45-0)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl 4-methoxybenzene-1-sulfonate (CAS 338402-41-8)
- 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol (CAS 142569-70-8)
- 2-[(2E)-2-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-ylidene}ethyl]-9,10-dihydroanthracene-9,10-dione (CAS 338961-95-8)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[2-(2-nitroethyl)phenyl]piperazine-1-carboxamide (CAS 339110-84-8)
- N-(5-chloro-2-methoxyphenyl)-2-(3,4-dichlorophenyl)quinoline-4-carboxamide (CAS 332176-51-9)
Recommended Standards
- 4-Chlorobenzyl 4-(3-(5-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)-3-oxopropyl)piperazine-1-carboxylate (CAS 1144035-43-7)
- Tris(2,2,3,3,3-pentafluoropropyl) borate (CAS 2003-04-5)
- Azimilide (CAS 149908-53-2)
- Dacomitinib Impurity 10 (CAS CATO-C4X-208610)
- 3-(5-Chloro-2-hydroxyphenyl)-2-methylacrylaldehyde (CAS 443872-86-4)
- Carbamic acid, [(4-hydroxybutyl)carbonimidoyl]bis-, bis(1,1-dimethylethyl) ester (CAS 208465-10-5)
- 4-(4-Fluorophenyl)butan-1-ol (CAS 40283-05-4)
- 2,2'-azanediylbis(ethan-1-ol) hemisulfate (CAS 20261-60-3)
- tert-Butyl 3-(4-bromophenyl)-3-oxopropanoate (CAS 1628222-76-3)
- [1,2,4]Triazolo[1,5-a]pyridine-7-methanamine (CAS 1313726-30-5)
- 2-(3-Hydroxypiperidin-1-yl)-1-(2-methylpiperidin-1-yl)ethan-1-one (CAS 1457953-03-5)
- Ethyl (E)-2-(2-bromoethylidene)hydrazine-1-carboxylate (CAS 62105-91-3)
- 2-Chloro-4-iodo-5-methylpyridine (CAS 1197957-18-8)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
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