Neratinib Impurity 11 CAS 1144516-16-4
| CAS No. | 1144516-16-4 |
| Molecular Formula | C32H36ClN7O3 |
| Molecular Weight | 602.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Neratinib Impurity 11 (CAS 1144516-16-4) is a certified pharmaceutical impurity reference standard with the molecular formula C32H36ClN7O3 and a molecular weight of 602.13 g/mol.
Based on its molecular formula C32H36ClN7O3, Neratinib Impurity 11 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 602.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Neratinib Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C32H36ClN7O3 |
| Molecular Weight | 602.13 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Neratinib Standards
- Neratinib Impurity 18 (CAS 1144516-17-5)
- Neratinib Impurity 6 (CAS CATO-C4X-11346)
- Neratinib Impurity 45 (CAS CATO-C4X-113445)
- Neratinib Impurity 53 (CAS CATO-C4X-113453)
- Neratinib Impurity 19 (CAS 1376619-98-5)
- Neratinib Impurity 35 (CAS CATO-C4X-113435)
- Neratinib Impurity 15 (CAS 1376615-55-2)
- Neratinib Impurity 16 (CAS 1376619-94-1)
Recommended Standards
- Cyclaniliprole (CAS 1031756-98-5)
- 2,5-Bis(perfluorobutyl)terephthalicacid (CAS 1621968-67-9)
- 8-Bromo-GTP (aqueous solution) (CAS 23197-98-0)
- Montelukast R-Sulfoxide (CAS 1152185-58-4)
- Cefoxitin Impurity 40 (CAS CATO-C4X-157840)
- Lenalidomide Impurity 60 (CAS 26581-81-7)
- Entecavir Impurity 50 (CAS CATO-C4X-107750)
- 2,4-Dihydroxybutanoic Acid (CAS 1518-62-3)
- MEthyl (2s)-2-amino-3-(furan-2-yl)propanoate (CAS 146725-85-1)
- 2-Amino-3-sulfopropanoic acid hydrochloride (CAS 20244-18-2)
- 4-Phenylbutyl 4-methylbenzenesulfonate (CAS 112775-09-4)
- (1S)-3,3'-Bis(3,5-bis(trifluoromethyl)phenyl)-[1,1'-binaphthalene]-2,2'-disulfonic acid (CAS 1216890-08-2)
- 3-(2,3-Difluorophenyl)azetidin-3-ol (CAS 1227617-02-8)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com