Telmisartan Impurity 12 CAS 114772-38-2
| CAS No. | 114772-38-2 |
| Molecular Formula | C15H13BrO2 |
| Molecular Weight | 305.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Telmisartan Impurity 12 (CAS 114772-38-2) is a certified pharmaceutical impurity reference standard with the molecular formula C15H13BrO2 and a molecular weight of 305.17 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, a polycyclic aromatic system, Telmisartan Impurity 12 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 305.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Telmisartan Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H13BrO2 |
| Molecular Weight | 305.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
Related Telmisartan Standards
- Telmisartan Impurity 40 (CAS 887583-89-3)
- Telmisartan EP Impurity A (CAS 152628-02-9)
- Telmisartan Impurity 87 (CAS CATO-C4X-135987)
- Telmisartan Impurity 65 (CAS CATO-C4X-135965)
- Telmisartan Impurity 63 (CAS CATO-C4X-135963)
- Telmisartan Impurity 94 (CAS CATO-C4X-135994)
- Telmisartan Impurity N2 (CAS 34981-09-4)
- Telmisartan Impurity 3 (CAS 133085-87-7)
Recommended Standards
- Tyrphostin AG 1024 (CAS 65678-07-1)
- Lumateperone Impurity 24 (CAS CATO-C4X-220124)
- rel-4-((2R,3R)-5-Bromo-3-methyl-2,3-dihydrobenzofuran-2-yl)phenol (CAS 2477608-95-8)
- Ozenoxacin Impurity 71 (CAS CATO-C4X-279671)
- Dacomitinib Impurity 47 (CAS CATO-C4X-208647)
- Melitracen Impurity 5 (CAS 111-18-2)
- Mirogabalin Impurity 93 (CAS CATO-C4X-292493)
- (R)-N-Ethylpyrrolidine-2-carboxamide hydrochloride (CAS 1956435-76-9)
- Methyl (2S,4S)-4-(2-naphthyloxy)-2-pyrrolidinecarboxylate (CAS 755707-37-0)
- Dodecylamineacetate (CAS 2016-56-0)
- 2-(Cyclopentyl(methyl)amino)acetamide (CAS 1090870-04-4)
- Methyl 2-bromo-4-fluoro-3-methylbenzoate (CAS 1805421-59-3)
- Ethyl 2-(2-chloropropanamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 632332-28-6)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com