Telmisartan EP Impurity H CAS 114772-40-6
| CAS No. | 114772-40-6 |
| Molecular Formula | C18H19BrO2 |
| Molecular Weight | 347.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Telmisartan EP Impurity H meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Telmisartan EP Impurity H (CAS 114772-40-6) is a certified pharmaceutical impurity reference standard with the molecular formula C18H19BrO2 and a molecular weight of 347.25 g/mol.
Owing to a steroid core, a hydroxyl group, an ether linkage, bromine substitution, Telmisartan EP Impurity H is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 347.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H19BrO2 |
| Molecular Weight | 347.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
Related Telmisartan Standards
- Telmisartan Impurity 24 (CAS 884330-17-0)
- Telmisartan Impurity 66 (CAS 885046-20-8)
- Telmisartan Impurity 90 (CAS CATO-C4X-135990)
- Telmisartan Impurity 92 (CAS CATO-C4X-135992)
- Telmisartan Impurity 22 (CAS 1797894-62-2)
- Telmisartan Impurity 42 (CAS 1860008-29-2)
- Telmisartan Impurity 43 (CAS 884330-18-1)
- Telmisartan Impurity N20 (CAS 1083158-65-9)
Recommended Standards
- N-Benzyl-N-(3-bromopyridin-2-yl)pivalamide (CAS 2055841-41-1)
- Propiconazole-d7 (CAS 1246818-14-3)
- N-(3-bromo-1-tetrahydropyran-2-yl-pyrazolo[4,3-c]pyridin-6-yl)acetamide (CAS 2708281-37-0)
- tert-Butyl N-{2-[2-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl}carbamate (CAS 1086600-36-3)
- N-Notroso Tedizolid impurity 106 (CAS CATO-C4X-1054106)
- Mivacurium chloride Impurity 48 (CAS CATO-C4X-137548)
- Perphenazine EP Impurity B (CAS 3533-97-9)
- 1-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)urea (CAS 59747-16-9)
- 2-Amino-5-[(4-bromophenyl)methyl]-5-(3-methoxyphenyl)-4,5-dihydro-1H-imidazol-4-one (CAS 1354924-37-0)
- 2-(Cyclopentyl(thiophen-3-ylmethyl)amino)acetonitrile (CAS 1482795-46-9)
- 3,4-Dichloro-2-fluorocinnamic acid (CAS 1807392-94-4)
- 4-Fluoro-N-hydroxybenzimidamide (CAS 22179-78-8)
- 3-(3-Oxo-3,4-dihydro-2h-1,4-benzothiazin-4-yl)propanoic acid (CAS 37012-79-6)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
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