Telmisartan Impurity 22 CAS 1797894-62-2
| CAS No. | 1797894-62-2 |
| Molecular Formula | C14H10Br2O2 |
| Molecular Weight | 370.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Telmisartan Impurity 22 (CAS 1797894-62-2), a pharmacopoeial impurity reference standard (molecular formula C14H10Br2O2, MW 370.04 g/mol) used for the identification and quantification of trace impurities in APIs.
Telmisartan Impurity 22 (C14H10Br2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H10Br2O2 |
| Molecular Weight | 370.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Br-containing |
Related Telmisartan Standards
- Telmisartan Impurity 17 (CAS 1352492-08-0)
- Telmisartan EP Impurity H (CAS 114772-40-6)
- Telmisartan Impurity 70 (CAS CATO-C4X-135970)
- Telmisartan Impurity 24 (CAS 884330-17-0)
- Telmisartan Impurity 66 (CAS 885046-20-8)
- Telmisartan Impurity 90 (CAS CATO-C4X-135990)
- Telmisartan Impurity 92 (CAS CATO-C4X-135992)
- Telmisartan Impurity 93 (CAS CATO-C4X-135993)
Recommended Standards
- Ambroxol Impurity 82 (CAS CATO-C4X-108582)
- Glumetinib Impurity 15 (CAS CATO-C4X-325915)
- 5-Bromo-2-((4-bromobenzyl)oxy)benzaldehyde (CAS 84102-43-2)
- N-(4-bromo-3-iodophenyl)thietan-3-amine (CAS 1865113-94-5)
- Trametinib Impurity 1 (CAS 871700-28-6)
- Gadobutrol impurity 176 (CAS CATO-C4X-2120176)
- Reserpine impurity 7 (CAS 482-85-9)
- (S)-(+)-Camptothecin (CAS 7689-03-4)
- 3-(5-Methyl-1,3,4-oxadiazol-2-yl)bicyclo[1.1.1]Pentan-1-amine (CAS 2336957-52-7)
- (S)-2'-(Dimethylphosphino)-N,N-dimethyl-[1,1'-binaphthalen]-2-amine (CAS 405928-70-3)
- Sodium phosphomolybdate hydrate (CAS 1313-30-0)
- {2-[1-(Phenylsulfonyl)piperidin-4-yl]ethyl}amine hydrochloride (CAS 1160245-35-1)
- Isothebaine (CAS 568-21-8)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com