Rotigotine EP Impurity H CAS 1148154-91-9
| CAS No. | 1148154-91-9 |
| Molecular Formula | C20H37NOS |
| Molecular Weight | 339.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rotigotine EP Impurity H is closely related to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Rotigotine EP Impurity H (CAS 1148154-91-9, C20H37NOS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, Rotigotine EP Impurity H is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 339.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rotigotine EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H37NOS |
| Molecular Weight | 339.58 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Rotigotine Standards
- rac-Rotigotine-D3 Methyl Ether Amide (CAS 1246814-64-1)
- rac-Rotigotine-D3 Methyl Ether (CAS 1246820-80-3)
- Rotigotine EP Impurity E (CAS 2708278-87-7)
- Rotigotine Racemate HCl (CAS 102120-99-0)
- Rotigotine Impurity 22 (CAS 1196459-54-7)
- Rotigotine Impurity 38 (CAS CATO-C4X-192738)
- Rotigotine (CAS 92206-54-7)
- Rotigotine (CAS 99755-59-6)
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- tert-Butyl (5-(N'-hydroxycarbamimidoyl)pyridin-2-yl)carbamate (CAS 1217885-82-9)
- Methyl 2-Nonynoate (CAS 111-80-8)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com