5-(t-Butyldimethylsilyloxy)-2-methoxyphenylboronic acid CAS 1150114-54-7
| CAS No. | 1150114-54-7 |
| Molecular Formula | C13H23BO4Si |
| Molecular Weight | 282.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(t-Butyldimethylsilyloxy)-2-methoxyphenylboronic acid.
CATO supplies 5-(t-Butyldimethylsilyloxy)-2-methoxyphenylboronic acid (CAS 1150114-54-7), a certified reference material (molecular formula C13H23BO4Si, MW 282.22 g/mol) for analytical method development and quality control.
The molecular framework of 5-(t-Butyldimethylsilyloxy)-2-methoxyphenylboronic acid (C13H23BO4Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H23BO4Si |
| Molecular Weight | 282.22 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.5 |
| CAS Registry Year (est.) | 1989 |
Related t Standards
- 6-[[2-(tert-Butyldimethylsilyloxy)ethyl]methylamino]pyridin-3-ol (CAS 326496-02-0)
- 6-Tert-Butyldimethylsilyloxy-4-(1-methylethenyl)-1-methyl-cyclohexane 1,2-epoxide (CAS 121289-19-8)
- 4-(tert-Butyldimethylsilyloxy)methyl-3-methylphenylboronic acid (CAS 2377608-40-5)
- 1-(tert-butyldimethylsilyloxy)-2-iodoethane (CAS 101166-65-8)
- 3-t-Butyldimethylsilyloxy-4-chlorophenylboronic acid (CAS 2096337-83-4)
- 5-(t-Butyldimethylsilyloxy)-2,3-difluorophenylboronic acid (CAS 1150114-45-6)
- 3-(t-Butyldimethylsilyloxy)-4,5-difluorophenylboronic acid (CAS 2377609-56-6)
- 4-(t-Butyldimethylsilyloxy)-2,3-difluorophenylboronic acid (CAS 870646-83-6)
Recommended Standards
- 4-Methyl-2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxylic acid (CAS 1119449-88-5)
- 3-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine (CAS 116233-20-6)
- 3-Phenoxy-5-(trifluoromethyl)picolinamide (CAS 1065607-72-8)
- (2S,6R)-1-(4-Bromobenzyl)-2,6-dimethylpiperidine (CAS 1200130-95-5)
- 2-Bromo-6-chloro-4-picoline (CAS 157329-89-0)
- 3-(3-Chloro-4-methoxyphenyl)propanoic acid (CAS 1857-56-3)
- 5-(4-Methoxyphenyl)-1-(phenylsulfonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole (CAS 887199-99-7)
- (2E)-1-(3-Chlorophenyl)-3-(4-fluorophenyl)prop-2-en-1-one (CAS 1801666-50-1)
- Boc-β-Lys(Z)-OH (dicyclohexylammonium) salt (CAS 401792-89-0)
- 5'-Amino-2'-methyl-[1,1'-biphenyl]-2-carboxylic acid (CAS 1181291-15-5)
- ethyl 2-(3-methoxybenzoyl)butanoate (CAS 1281557-09-2)
- 4-(4-(Dimethylamino)phenyl)-N-(3-fluorophenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide (CAS 421567-27-3)
- 4-(2-(5-Ethyl-1,3,4-oxadiazol-2-yl)ethyl)aniline (CAS 689251-59-0)
- Semaglutide impurity 210 (CAS CATO-C4X-2226210)
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