4-(tert-Butyldimethylsilyloxy)methyl-3-methylphenylboronic acid CAS 2377608-40-5
| CAS No. | 2377608-40-5 |
| Molecular Formula | C14H25BO3Si |
| Molecular Weight | 280.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 280.24 g/mol gives 4-(tert-Butyldimethylsilyloxy)methyl-3-methylphenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(tert-Butyldimethylsilyloxy)methyl-3-methylphenylboronic acid (CAS 2377608-40-5), molecular formula C14H25BO3Si and molecular weight 280.24 g/mol, is a CATO reference standard with documented purity and traceability.
4-(tert-Butyldimethylsilyloxy)methyl-3-methylphenylboronic acid (C14H25BO3Si) contains a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(tert-Butyldimethylsilyloxy)methyl-3-methylphenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H25BO3Si |
| Molecular Weight | 280.24 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.5 |
| CAS Registry Year (est.) | 1999 |
Related tert Standards
- 5-(t-Butyldimethylsilyloxy)-2-methoxyphenylboronic acid (CAS 1150114-54-7)
- 6-[[2-(tert-Butyldimethylsilyloxy)ethyl]methylamino]pyridin-3-ol (CAS 326496-02-0)
- 6-Tert-Butyldimethylsilyloxy-4-(1-methylethenyl)-1-methyl-cyclohexane 1,2-epoxide (CAS 121289-19-8)
- 1076199-66-0 3-(tert-Butyldimethylsilyloxy)-5-(1-methylamino)-5-oxopentanoic Acid 3-[(1,1-Dimethylethyl)dimethylsilyloxy]-5-(1-methylamino)-5-oxopentanoic Acid (CAS 1076199-66-0)
- 1-(tert-butyldimethylsilyloxy)-2-iodoethane (CAS 101166-65-8)
- 3-t-Butyldimethylsilyloxy-4-chlorophenylboronic acid (CAS 2096337-83-4)
- 5-(t-Butyldimethylsilyloxy)-2,3-difluorophenylboronic acid (CAS 1150114-45-6)
- 3-(t-Butyldimethylsilyloxy)-4,5-difluorophenylboronic acid (CAS 2377609-56-6)
Recommended Standards
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- 4-((3-(Trifluoromethyl)benzyl)oxy)benzaldehyde (CAS 70627-18-8)
- 4,4,4-Trifluoro-3-methylbutan-1-ol (CAS 339-62-8)
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- 4-(2-NITROPHENOXY)BENZAMIDE (CAS 106163-99-9)
- N-(2-Chloro-5-(trifluoromethyl)phenyl)-2-((5-((4-fluorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 477333-35-0)
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- Mast Cell Degranulating (MCD) Peptide HR-2 (CAS 80388-04-1)
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