4,7-Dichloro-8-fluoro-2-(trifluoromethyl)quinoline CAS 1150164-86-5
| CAS No. | 1150164-86-5 |
| Molecular Formula | C10H3Cl2F4N |
| Molecular Weight | 284.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4,7-Dichloro-8-fluoro-2-(trifluoromethyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4,7-Dichloro-8-fluoro-2-(trifluoromethyl)quinoline (CAS 1150164-86-5) is a high-purity analytical reference standard with the molecular formula C10H3Cl2F4N and a molecular weight of 284.04 g/mol.
The molecular framework of 4,7-Dichloro-8-fluoro-2-(trifluoromethyl)quinoline (C10H3Cl2F4N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H3Cl2F4N |
| Molecular Weight | 284.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 1-(Difluoromethoxy)-4-iodo-2-methylbenzene (CAS 1062613-63-1)
- 1-(2,2-Difluoroethoxy)-2-iodobenzene (CAS 1160495-81-7)
- 6,7-Dimethoxy-1-(4-nitrobenzyl)-3,4-dihydroisoquinoline (CAS 10268-39-0)
- 2-(Difluoromethoxy)-4-iodo-1-methylbenzene (CAS 1201196-39-5)
- 1-(3-chlorophenyl)-5-methyl-1H-pyrazol-3-amine (CAS 1248180-56-4)
- 3-Iodo-4-(trifluoromethyl)aniline hydrochloride (CAS 2185590-32-1)
- 1-(4-Chlorophenyl)-2-(pyridin-3-yl)ethan-1-one (CAS 58158-57-9)
- 2-Chloro-6,7-difluoroquinoline-3-carbaldehyde (CAS 209909-13-7)
- 5-Methyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid (CAS 854405-74-6)
- 1-(2-Methylbenzyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 1497456-40-2)
- n-Isobutyl-2-(methylsulfonyl)aniline (CAS 1156233-57-6)
- Tert-butyl 4-benzyl-3,3-difluoropiperidine-1-carboxylate (CAS 1334414-67-3)
- Doxorubicin Impurity 15 (CAS 59325-97-2)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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