8-Chloro-3-fluoro-[1,5]naphthyridine CAS 1151802-02-6
| CAS No. | 1151802-02-6 |
| Molecular Formula | C8H14ClFN2 |
| Molecular Weight | 192.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.66 g/mol gives 8-Chloro-3-fluoro-[1,5]naphthyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 8-Chloro-3-fluoro-[1,5]naphthyridine (CAS 1151802-02-6), a certified reference material (molecular formula C8H14ClFN2, MW 192.66 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H14ClFN2, 8-Chloro-3-fluoro-[1,5]naphthyridine contains a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic molecular-ion distribution patterns in mass spectrometry. The molecular weight of 192.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14ClFN2 |
| Molecular Weight | 192.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-chloro-7-fluoroquinoxaline (CAS 1233932-59-6)
- 4-chloro-8-fluoroquinazoline (CAS 124429-27-2)
- 5-chloro-8-fluoro-1,6-naphthyridine (CAS 1374652-06-8)
- 2-chloro-5-fluoro-quinazoline (CAS 1388028-12-3)
- 4-chloro-5-fluoroquinazoline (CAS 16499-60-8)
- 1-chloro-6-fluorophthalazine (CAS 23928-55-4)
- 2-chloro-6-fluoro-1,7-naphthyridine (CAS 2089054-23-7)
- 8-chloro-5-fluoro-1,7-naphthyridine (CAS 2306271-19-0)
Recommended Standards
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- {7-chloro-[1,2,4]triazolo[4,3-c]pyrimidin-3-yl}methanol (CAS 1183462-18-1)
- Methyl 2-acetyl-5-chloropentanoate (CAS 89118-13-8)
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- 3-(2-(Pyrrolidin-1-yl)thiazol-4-yl)aniline (CAS 1193078-21-5)
- 4-(oxan-4-yl)-2-(piperidin-4-yl)pyrimidine dihydrochloride (CAS 2059942-36-6)
- N-Benzyl-4-chloro-N-cyclohexylbenzamide (CAS 945714-67-0)
- Bifonazole-D5 (CAS CATO-C4X-156024)
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