1-(3-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid CAS 1152511-49-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1152511-49-3
Molecular FormulaC10H7FN2O3
Molecular Weight222.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(3-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid CAS 1152511-49-3 chemical structure

Description

The occurrence of 1-(3-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(3-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (CAS 1152511-49-3), molecular formula C10H7FN2O3 and molecular weight 222.17 g/mol, is a CATO reference standard with documented purity and traceability.

1-(3-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (C10H7FN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H7FN2O3
Molecular Weight222.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF-containing
Nitrogen Atoms2

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