1-(4-Fluorophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid CAS 1204296-62-7
| CAS No. | 1204296-62-7 |
| Molecular Formula | C10H7FN2O3 |
| Molecular Weight | 222.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 222.17 g/mol gives 1-(4-Fluorophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(4-Fluorophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid (CAS 1204296-62-7), molecular formula C10H7FN2O3 and molecular weight 222.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(4-Fluorophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid (C10H7FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4-Fluorophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7FN2O3 |
| Molecular Weight | 222.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 1-[(4-Fluorophenyl)methyl]imidazolidine-2,4,5-trione (CAS 105686-00-8)
- 1-(3-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (CAS 1152511-49-3)
- 1-(2-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (CAS 1152602-04-4)
- 1-(4-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (CAS 1152602-19-1)
- 1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-4-carboxylic acid (CAS 1204297-01-7)
- 1-(2-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-4-carboxylic acid (CAS 1204297-73-3)
- 1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid (CAS 1251384-99-2)
- 5-[(2-fluorophenyl)methyl]-1,2,4-oxadiazole-3-carboxylic acid (CAS 1339354-36-7)
Recommended Standards
- 6-Fluoro-4-hydroxy-2-methyl-3-nitroquinoline (CAS 1203578-88-4)
- Methyl 6-fluoro-4-oxo-4h-chromene-2-carboxylate (CAS 116543-91-0)
- 2-(4-Amino-1h-pyrazol-1-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1153735-51-3)
- 2-(3-Amino-1h-pyrazol-1-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1247340-56-2)
- 2,4-Difluoro-3-methoxyaniline (CAS 886499-08-7)
- Ac-Arg-Gly-Lys(Ac)-AMC (CAS 660846-97-9)
- N-(4-Chlorophenyl)-2-(4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl)acetamide (CAS 684234-56-8)
- Ethyl 2-amino-4-bromothiazole-5-carboxylate (CAS 1353102-10-9)
- Isoselenocyanatobenzene (CAS 4426-68-0)
- 5-[1-(dimethylamino)propyl]-4-[2-(morpholin-4-yl)ethyl]-4H-1,2,4-triazole-3-thiol (CAS 879362-32-0)
- Elinogrel (CAS 936500-94-6)
- 3-cyclopropyl-2-mercaptopyrido[2,3-d]pyrimidin-4(3H)-one (CAS 688793-42-2)
- 1-(4-Fluorophenyl)-3-(2-(methylamino)ethyl)urea (CAS 1248083-18-2)
- Tau Peptide (275-305) (Repeat 2 Domain) trifluoroacetate salt (CAS 330456-25-2)
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