1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid CAS 1251384-99-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1251384-99-2
Molecular FormulaC10H7FN2O3
Molecular Weight222.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid CAS 1251384-99-2 chemical structure

Description

The occurrence of 1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid (CAS 1251384-99-2) is a high-purity analytical reference standard with the molecular formula C10H7FN2O3 and a molecular weight of 222.17 g/mol.

The molecular framework of 1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid (C10H7FN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Fluorophenyl)-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H7FN2O3
Molecular Weight222.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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