Methyl 2-(1-(2-chlorophenyl)-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)acetate CAS 1158233-60-3
| CAS No. | 1158233-60-3 |
| Molecular Formula | C12H11ClN2O3 |
| Molecular Weight | 266.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 2-(1-(2-chlorophenyl)-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)acetate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 2-(1-(2-chlorophenyl)-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)acetate (CAS 1158233-60-3), molecular formula C12H11ClN2O3 and molecular weight 266.68 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 2-(1-(2-chlorophenyl)-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)acetate (C12H11ClN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 2-(1-(2-chlorophenyl)-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11ClN2O3 |
| Molecular Weight | 266.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 2-(1-(2-Chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)acetic acid (CAS 1015844-43-5)
- 2-(1-(4-Chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)acetic acid (CAS 1015844-49-1)
- 2-(5-(((4-Chlorophenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)acetic acid (CAS 1087648-35-8)
- Methyl 2-(1-(3-chlorophenyl)-5-hydroxy-1H-pyrazol-3-yl)acetate (CAS 1158589-04-8)
- 1-(4-Chlorophenyl)-N-methyl-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1300712-92-8)
- Ethyl 2-(4-chlorophenyl)-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate (CAS 1326923-49-2)
- 1-(3-Chlorophenyl)-5-methoxy-4-methyl-1H-pyrazole-3-carboxylic acid (CAS 274253-32-6)
- 1-(4-Chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1h-imidazol-2-yl)urea (CAS 58030-63-0)
Recommended Standards
- Ethyl 5-amino-1-(2-chlorophenyl)-1H-1,2,3-triazole-4-carboxylate (CAS 106748-15-6)
- Ethyl 4-chloro-7-methoxyquinazoline-2-carboxylate (CAS 1189107-22-9)
- 2-(2-Chlorophenoxy)-N-(4h-1,2,4-triazol-3-yl)propanamide (CAS 1050829-61-2)
- 1-(5-Chloro-6-methylbenzo[d]oxazol-2-yl)azetidine-3-carboxylic acid (CAS 1206970-04-8)
- 5-Bromo-2-chloropyridine-4-boronic acid, pinacol ester (CAS 2121514-81-4)
- N-Desethyl-E-Clomiphene HCl (CAS 21625-70-7)
- Tert-butyl (1R,5S)-6-(aminomethyl)-3-azabicyclo[3.1.1]Heptane-3-carboxylate (CAS 1341038-22-9)
- 3-Hydroxy-4-(methoxycarbonyl)benzoic acid (CAS 808123-00-4)
- 2-Methyl-2-propanyl 4-nitro-11-azatricyclo[6.2.1.02,7]undeca-2,4,6-triene-11-carboxylate (CAS 942492-08-2)
- 1-(Sec-butyl)-4-nitrobenzene (CAS 4237-40-5)
- 2-Methyl-5-nitroisoindoline (CAS 500546-49-6)
- Ethyl 5-(4-fluorophenyl)thiazole-4-carboxylate (CAS 127918-22-3)
- [(3,4-Dichlorophenyl)methyl](propan-2-yl)amine hydrochloride (CAS 90944-00-6)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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