1-(3-Chlorophenyl)-5-methoxy-4-methyl-1H-pyrazole-3-carboxylic acid CAS 274253-32-6
| CAS No. | 274253-32-6 |
| Molecular Formula | C12H11ClN2O3 |
| Molecular Weight | 266.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(3-Chlorophenyl)-5-methoxy-4-methyl-1H-pyrazole-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1-(3-Chlorophenyl)-5-methoxy-4-methyl-1H-pyrazole-3-carboxylic acid (CAS 274253-32-6), a certified reference material (molecular formula C12H11ClN2O3, MW 266.68 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H11ClN2O3, 1-(3-Chlorophenyl)-5-methoxy-4-methyl-1H-pyrazole-3-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 266.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11ClN2O3 |
| Molecular Weight | 266.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 2-(1-(2-Chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)acetic acid (CAS 1015844-43-5)
- 2-(1-(4-Chlorophenyl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl)acetic acid (CAS 1015844-49-1)
- 2-(5-(((4-Chlorophenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)acetic acid (CAS 1087648-35-8)
- Methyl 2-(1-(2-chlorophenyl)-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)acetate (CAS 1158233-60-3)
- Methyl 2-(1-(3-chlorophenyl)-5-hydroxy-1H-pyrazol-3-yl)acetate (CAS 1158589-04-8)
- 1-(4-Chlorophenyl)-N-methyl-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1300712-92-8)
- Ethyl 2-(4-chlorophenyl)-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate (CAS 1326923-49-2)
- 1-(4-Chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1h-imidazol-2-yl)urea (CAS 58030-63-0)
Recommended Standards
- 1-(3-Chloro-4-methylphenyl)-6-oxo-1,4,5,6-tetrahydropyridazine-3-carboxylic acid (CAS 731795-80-5)
- 1-(4-Chloro-3-methylphenoxymethyl)-1h-pyrazole-3-carboxylic acid (CAS 957400-47-4)
- (R)-3-(6-Chloro-1H-indol-3-yl)-2-formamidopropanoic acid (CAS 57233-89-3)
- (4-Chloro-3-nitrophenyl)(3,6-dihydropyridin-1(2H)-yl)methanone (CAS 648409-36-3)
- 2-(5-Chloro-2-thienyl)-3-methylpyridine (CAS 1187170-17-7)
- 4-(Butan-2-yl)benzaldehyde (CAS 28293-43-8)
- 2-(2-Aminoethyl)-1H-isoindole-1,3(2H)-dione trifluoroacetate (CAS 1965304-60-2)
- N,N-dimethylpyrazin-2-amine (CAS 5214-29-9)
- Abz-Amyloid β/A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide trifluoroacetate salt (CAS 1182723-43-8)
- 2,5-Dioxo-2,5-dihydrofuran-3,4-diyl diacetate (CAS 132-79-6)
- 7-Hydroxy Perphenazine (CAS 52174-38-6)
- Calcitonin Impurity 12 (CAS CATO-C4X-221812)
- (R)-3-[(tert-Butyldimethylsilyl)oxy]piperidine (CAS 1416807-31-2)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
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