Trimipramine EP Impurity C HCI CAS 1159-80-4
| CAS No. | 1159-80-4 |
| Molecular Formula | C20H24N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Trimipramine EP Impurity C HCI (CAS 1159-80-4, C20H24N2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Trimipramine EP Impurity C HCI (C20H24N2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 328.88 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H24N2 HCl |
| Molecular Weight | 328.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trimipramine Standards
- Trimipramine EP Impurity B (CAS 10464-24-1)
- Trimipramine-d3 Maleate (CAS 1185245-93-5)
- Trimipramine-D (CAS 136765-54-3)
- Trimipramine Maleate EP Impurity A (CAS 14171-70-1)
- Trimipramine Maleate EP Impurity G (CAS 150802-55-4)
- Trimipramine Impurity 3 (CAS 2064-15-5)
- Trimipramine Maleate EP Impurity B (CAS 2293-21-2)
- Trimipramine EP Impurity C (CAS 315-69-5)
Recommended Standards
- Sitafloxacin Dechloro Impurity Hydrochloride (CAS CATO-C4X-115550)
- Progesterone Impurity 96 (CAS CATO-C4X-150296)
- Lorazepam Impurity 8 (CAS 2848-96-6)
- 1-(3-Methoxybenzyl)piperazin-2-one (CAS 893747-81-4)
- 2-chloro-3-[2,6-dichloro-4-(trifluoromethyl)phenyl]propanenitrile (CAS 258518-45-5)
- 2-Chloro-4-(4-t-butylphenyl)benzoic acid (CAS 1261955-02-5)
- 3-(4-(4-Chlorophenyl)-2-(2-methyl-1H-imidazol-1-yl)oxazol-5-yl)propan-1-ol (CAS 198064-22-1)
- 2-(4-Chloro-2,6-dimethylphenoxy)acetic acid (CAS 39944-18-8)
- 2-(4-chloro-2-methylphenoxy)(3-pyridyl) 4-benzylpiperazinyl ketone (CAS 497060-64-7)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com