Anagrelide Impurity 12 CAS 1159977-03-3
| CAS No. | 1159977-03-3 |
| Molecular Formula | C10H9Cl2N3O2 |
| Molecular Weight | 274.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Anagrelide Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Anagrelide Impurity 12 (CAS 1159977-03-3, C10H9Cl2N3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C10H9Cl2N3O2, Anagrelide Impurity 12 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 274.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H9Cl2N3O2 |
| Molecular Weight | 274.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Anagrelide Standards
- Anagrelide Impurity 45 (CAS CATO-C4X-224045)
- Anagrelide Impurity 3 (CAS 6379-46-0)
- Anagrelide USP Related Compound A (CAS 70406-92-7)
- Anagrelide Impurity 32 (CAS 70380-52-8)
- Anagrelide-13C3 (CAS 1219531-58-4)
- Anagrelide impurity 25 (CAS 1092352-99-2)
- Anagrelide (CAS 68475-42-3)
- Anagrelide Impurity 26 (CAS 742010-46-4)
Recommended Standards
- tert-Butyl (3-bromo-2,2-difluoropropyl)carbamate (CAS 2353309-16-5)
- Cyclanilide (CAS 113136-77-9)
- Methyl 5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxylate (CAS 851785-48-3)
- 2-Bromo-N-(3,5-dimethoxyphenyl)acetamide (CAS 1009562-40-6)
- Palbociclib Impurity 166 (CAS CATO-C4X-1125166)
- Nicorandil Impurity 45 formate salt (CAS 2365474-05-9（free base）)
- Sorbitol Impurity 5 (CAS CATO-C4X-25325)
- 3-[(4-Bromo-2-isopropylphenoxy)methyl]piperidinehydrochloride (CAS 1220021-03-3)
- D-Glucamine (CAS 488-43-7)
- 1-Methyl-1H-pyrrole-3,4-dicarboxylic acid (CAS 86731-91-1)
- cis-3-Amino-1-hydroxy-4-methylpyrrolidin-2-one (CAS 132619-43-3)
- Boc-Glu(OcHex)-OH (CAS 73821-97-3)
- 4-Chlorobenzenecarbaldehyde oxime (CAS 3848-36-0)
- Endo-Gly29-Tirzepatide (CAS CATO-CPTD788685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com