Methyl 5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxylate CAS 851785-48-3
| CAS No. | 851785-48-3 |
| Molecular Formula | C11H9Cl2NO3 |
| Molecular Weight | 274.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxylate (CAS 851785-48-3) is a high-purity analytical reference standard with the molecular formula C11H9Cl2NO3 and a molecular weight of 274.10 g/mol.
Based on its molecular formula C11H9Cl2NO3, Methyl 5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 274.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 5,7-dichloro-1-oxo-1,2,3,4-tetrahydroisoquinoline-6-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9Cl2NO3 |
| Molecular Weight | 274.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 2-(4,5-Dichloro-1H-imidazol-1-yl)-N-(furan-2-ylmethyl)acetamide (CAS 1219567-37-9)
- 5-((2,4-Dichloro-6-methylphenoxy)methyl)-1,3,4-oxadiazol-2-amine (CAS 1706439-55-5)
- 6,7-Dichloro-2,3-dimethoxyquinoxalin-5-amine (CAS 178619-89-1)
- 2-(2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-methylpropanoic acid (CAS 2306276-45-7)
- 2,8-Dichloro-6,7-dimethoxyquinazolin-4-amine (CAS 79572-01-3)
- 3-(2-(4,5-Dichloro-1H-imidazol-1-yl)ethyl)-3-azabicyclo[3.1.0]Hexane-2,4-dione (CAS 866151-57-7)
- 4,5-Dichloro-6-methoxy-1-methyl-1H-indole-2-carboxylic acid (CAS 2131751-70-5)
- Ethyl 5,7-dichloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 876391-25-2)
Recommended Standards
- tert-Butyl (3-bromo-2,2-difluoropropyl)carbamate (CAS 2353309-16-5)
- Bis-trifluoroethyl Ethylphosphonate (CAS 650-16-8)
- Anagrelide Impurity 12 (CAS 1159977-03-3)
- 5-Iodo-2-(pyrrolidin-1-yl)pyridine (CAS 494771-62-9)
- 2-{[(3-fluorophenyl)methyl]sulfanyl}-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole (CAS 477857-07-1)
- ethyl 3-methyl-6-oxo-1,7-dihydropyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018166-61-4)
- 4-(3-(1H-Imidazol-1-yl)propyl)thiomorpholine 1,1-dioxide (CAS 477858-48-3)
- 1-(4-Butoxybenzoyl)-4-{[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (CAS 1775482-34-2)
- 2-Methyl-3-(trifluoromethyl)benzenesulfonyl chloride (CAS 1191545-46-6)
- (R)-2-Amino-3-(3-ethoxy-5-methylisoxazol-4-yl)propanoic acid (CAS 740059-30-7)
- N-(2,4-difluorophenyl)-6-(isopropylthio)nicotinamide (CAS 339030-46-5)
- 2-(Cyclopropyl(2,4-dichlorobenzyl)amino)ethanol (CAS 1249729-45-0)
- Trichlorfon (CAS 52-68-6)
- FLAG Epitope Peptide (CAS 98849-88-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com