Daunorubicin Impurity 1 CAS 1159977-24-8
| CAS No. | 1159977-24-8 |
| Molecular Formula | C19H12O7 |
| Molecular Weight | 352.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Daunorubicin Impurity 1 (CAS 1159977-24-8) is a certified pharmaceutical impurity reference standard with the molecular formula C19H12O7 and a molecular weight of 352.29 g/mol.
The molecular framework of Daunorubicin Impurity 1 (C19H12O7) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H12O7 |
| Molecular Weight | 352.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Related Daunorubicin Standards
- Daunorubicin Impurity N3 (CAS 32434-04-1)
- Daunorubicin EP Impurity E (CAS 28008-51-7)
- Daunorubicin Impurity 1 (CAS 51996-45-3)
- Daunorubicin Impurity N3 (CAS 29742-69-6)
- Daunorubicin Impurity 16 (CAS CATO-C4X-193716)
- Daunorubicin Impurity 10 (CAS 76034-18-9)
- 3-epi-Daunorubicin (CAS 66322-65-4)
- epi-Daunorubicin (CAS 57918-24-8)
Recommended Standards
- Diacerein Impurity 17 (CAS 65209-90-7)
- Daphnoretin (CAS 2034-69-7)
- 6160-80-1 4-methylumbelliferone beta-D-glucuronide 4-MUG 4-Methylumbelliferyl glucuronide 4-methyl-2-oxo-2H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acid 4-Methylumbelliferyl beta-glucuronide 4-Methylumbelliferone glucuronide CHEBI:1904 (CAS 6160-80-1)
- 2,5-Dichloro-N-[4-(hexyloxy)benzyl]aniline (CAS 1040683-91-7)
- Nifedipine EP Impurity D (CAS 14205-39-1)
- Pyrazoloquinolone Impurity 4 (CAS CATO-C4X-23894)
- Topiroxostat Impurity 49 (CAS 14906-59-3)
- Methyl 3-chloro-5-iodo-2-methylbenzoate (CAS 1692477-05-6)
- 2-Bromo-5-ethoxybenzaldehyde (CAS 43192-32-1)
- 3-(Difluoromethyl)-5-methoxy-2-(trifluoromethyl)pyridin-4-amine (CAS 1804683-05-3)
- 1-Tosyl-2,3,6,7-tetrahydro-1H-azepine (CAS 57502-57-5)
- 3-bromo-1H-pyrrole-2-carbaldehyde (CAS 408359-07-9)
- (S)-6-(tert-Butoxycarbonyl)-6-azaspiro[3.4]octane-7-carboxylic acid (CAS 1980007-51-9)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com