Daunorubicin EP Impurity E CAS 28008-51-7
| CAS No. | 28008-51-7 |
| Molecular Formula | C21H20O8 |
| Molecular Weight | 400.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Daunorubicin EP Impurity E (CAS 28008-51-7, C21H20O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Daunorubicin EP Impurity E (C21H20O8) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 400.38 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Daunorubicin EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H20O8 |
| Molecular Weight | 400.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
Related Daunorubicin Standards
- Daunorubicin Impurity N3 (CAS 32434-04-1)
- Daunorubicin Impurity 1 (CAS 1159977-24-8)
- Daunorubicin Impurity N3 (CAS 29742-69-6)
- Daunorubicin Impurity 16 (CAS CATO-C4X-193716)
- Daunorubicin Impurity 10 (CAS 76034-18-9)
- 3-epi-Daunorubicin (CAS 66322-65-4)
- epi-Daunorubicin (CAS 57918-24-8)
- Daunorubicin EP Impurity B ((S)-Isomer) (CAS 28008-55-1)
Recommended Standards
- Minocycline impurity 75 (CAS 803616-67-3)
- Etoposide EP Impurity L (CAS 40505-27-9)
- Methotrexate Impurity 35 (CAS CATO-C4X-115435)
- Etoposide Impurity 29 (CAS CATO-C4X-202429)
- Cefixime Impurity 36 (CAS CATO-C4X-113936)
- Metformin Impurity 107 (CAS CATO-C4X-1065107)
- Risdiplam Impurity 3 (CAS CATO-C4X-30123)
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- Gibberellenic Acid (CAS 546-09-8)
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- 7-(Piperidin-1-ylmethyl)quinolin-8-ol (CAS 6632-09-3)
- Tau Peptide (74-102) (Exon 3/Insert 2 Domain) trifluoroacetate salt (CAS 1322695-34-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com