Bicalutamide EP Impurity B CAS 1159977-36-2
| CAS No. | 1159977-36-2 |
| Molecular Formula | C18H14F4N2O4S |
| Molecular Weight | 430.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Bicalutamide EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Bicalutamide EP Impurity B (CAS 1159977-36-2), a pharmacopoeial impurity reference standard (molecular formula C18H14F4N2O4S, MW 430.37 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Bicalutamide EP Impurity B is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 430.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H14F4N2O4S |
| Molecular Weight | 430.37 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bicalutamide Standards
- (S)-Bicalutamide (CAS 113299-38-0)
- Bicalutamide impurity A (CAS 113299-40-4)
- Bicalutamide EP Impurity H (CAS 2512198-58-0)
- Bicalutamide Impurity 5 (CAS 1166228-30-3)
- Bicalutamide (CAS 90357-06-5)
- (R)-Bicalutamide-d4 (CAS 1217826-87-3)
- Bicalutamide Impurity 28 (CAS CATO-C4X-101328)
- Bicalutamide USP Related Compound A (CAS 945419-64-7)
Recommended Standards
- Nicardipine Impurity 63 (CAS CATO-C4X-171063)
- Ac4ManNAz (CAS 361154-30-5)
- Ac4GalNAz (CAS 653600-56-7)
- 2,6-Bis((4,6-dimethoxypyrimidin-2-yl)oxy)benzoic Acid (CAS 125401-75-4)
- Fenofibrate EP Impurity E (CAS 42019-07-8)
- Elagolix Impurity 66 (CAS CATO-C4X-206866)
- Epirubicin EP Impurity G (Epirubicin Dimer) (CAS 1046827-43-3)
- 3-Fluoro-6H-benzo[c]chromen-6-one (CAS 7509-00-4)
- 3-{[3-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)propyl]amino}propyl carbamimidothioate dihydrobromide 3678-72-6 AR-1F1323 (CAS 3678-72-6)
- (3-(Tert-butyl)-1,2,4-oxadiazol-5-yl)methanamine hydrochloride (CAS 1185081-01-9)
- 2-(Methylthio)-6-(pyridin-3-yl)pyrimidin-4(3H)-one (CAS 1184919-66-1)
- 3-Butylphthalide-d9 (CAS CATO-C3D-5711)
- N1-(3-Fluoro-4-methylphenyl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide (CAS 900001-30-1)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com