Fenofibrate EP Impurity E CAS 42019-07-8
| CAS No. | 42019-07-8 |
| Molecular Formula | C18H17ClO4 |
| Molecular Weight | 332.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Fenofibrate EP Impurity E is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Fenofibrate EP Impurity E (CAS 42019-07-8) is a certified pharmaceutical impurity reference standard with the molecular formula C18H17ClO4 and a molecular weight of 332.78 g/mol.
Fenofibrate EP Impurity E (C18H17ClO4) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fenofibrate EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17ClO4 |
| Molecular Weight | 332.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
Related Fenofibrate Standards
- Fenofibrate Impurity 16 (CAS CATO-C4X-101816)
- Fenofibrate Impurity 14 (CAS CATO-C4X-164314)
- Fenofibrate EP Impurity B-d6 (Fenofibric Acid-d6) (CAS 1092484-69-9)
- Fenofibrate Impurity 33 (CAS 62809-68-1)
- Fenofibrate Impurity N113 (CAS 60012-96-6)
- Fenofibrate Impurity 2 (CAS 62809-66-9)
- Fenofibrate Impurity 17 (CAS CATO-C4X-164317)
- Fenofibrate Impurity 17 (CAS CATO-C4X-101817)
Recommended Standards
- Theophylline Impurity 6 (CAS 81781-90-0)
- Empagliflozin impurity 215 (CAS 2452301-37-8)
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- 1,2,4-Tribromo-5-fluorobenzene (CAS 7655-70-1)
- Azithromycin Impurity 33 (CAS CATO-C4X-100333)
- Nafamostat impurity 84 (CAS 82955-97-3)
- Vardenafil Impurity 58 (CAS CATO-C4X-101758)
- 1-chloro-6-fluorophthalazine (CAS 23928-55-4)
- 3-(2-Methylpyrimidin-4-yl)benzoic acid (CAS 924859-13-2)
- Octan-1-amine hydrochloride (CAS 142-95-0)
- 3-(4-Chlorophenyl)-3-(4-hydroxyphenyl)isobenzofuran-1(3H)-one (CAS 116143-36-3)
- 3-Iodo-4-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1190313-65-5)
- 3-Methoxy-6-(thiophen-2-yl)pyridazine (CAS 68206-17-7)
- Vialox Peptide(Pentapeptide-3) diacetate (CAS 725232-44-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com