Methyl 6-Chloro-2-(thiophen-2-yl)pyrimidine-4-carboxylate CAS 1159979-32-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1159979-32-4
Molecular FormulaC10H7ClN2O2S
Molecular Weight254.69 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 6-Chloro-2-(thiophen-2-yl)pyrimidine-4-carboxylate CAS 1159979-32-4 chemical structure

Description

CATO manufactures Methyl 6-Chloro-2-(thiophen-2-yl)pyrimidine-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Methyl 6-Chloro-2-(thiophen-2-yl)pyrimidine-4-carboxylate (CAS 1159979-32-4) is a high-purity analytical reference standard with the molecular formula C10H7ClN2O2S and a molecular weight of 254.69 g/mol.

The molecular framework of Methyl 6-Chloro-2-(thiophen-2-yl)pyrimidine-4-carboxylate (C10H7ClN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC10H7ClN2O2S
Molecular Weight254.69 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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