2-Hydroxy-5-oxo-Rivaroxaban CAS 1160169-96-9
| CAS No. | 1160169-96-9 |
| Molecular Formula | C19H28ClN3O6S |
| Molecular Weight | 461.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 461.96 g/mol gives 2-Hydroxy-5-oxo-Rivaroxaban distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Hydroxy-5-oxo-Rivaroxaban (CAS 1160169-96-9) is a high-purity analytical reference standard with the molecular formula C19H28ClN3O6S and a molecular weight of 461.96 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Hydroxy-5-oxo-Rivaroxaban is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 461.96 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Hydroxy-5-oxo-Rivaroxaban meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H28ClN3O6S |
| Molecular Weight | 461.96 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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