Dasatinib Impurity 45 CAS 1025814-13-4
| CAS No. | 1025814-13-4 |
| Molecular Formula | C20H24ClN7O2S |
| Molecular Weight | 461.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Dasatinib Impurity 45 (CAS 1025814-13-4) is a certified pharmaceutical impurity reference standard with the molecular formula C20H24ClN7O2S and a molecular weight of 461.97 g/mol.
Based on its molecular formula C20H24ClN7O2S, Dasatinib Impurity 45 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 461.97 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H24ClN7O2S |
| Molecular Weight | 461.97 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib Impurity 38 (CAS 1159977-25-9)
- Dasatinib Impurity 28 (CAS 1184919-23-0)
- Dasatinib Impurity 72 (CAS CATO-C4X-160772)
- Dasatinib Impurity 34 (CAS CATO-C4X-160734)
- Dasatinib Impurity 35 (CAS CATO-C4X-160735)
- Dasatinib Impurity 57 (CAS 2135905-86-9)
- Dasatinib Impurity 3 (CAS 910297-51-7)
- Dasatinib (CAS 302962-49-8)
Recommended Standards
- 2-Hydroxy-5-oxo-Rivaroxaban (CAS 1160169-96-9)
- tert-Butyl 4-(1-(tert-butoxycarbonyl)-5-(3-chlorophenyl)-1H-pyrazol-3-yl)piperidine-1-carboxylate (CAS 1956370-59-4)
- 2-Iodoperfluoro(5-methyl-4-oxahexane) (CAS 16005-45-1)
- 4-(6-{[(4-chlorophenyl)sulfanyl]methyl}-2-{[(4-fluorophenyl)methyl]sulfanyl}pyrimidin-4-yl)morpholine (CAS 341965-47-7)
- Arbidol Impurity 56 (CAS CATO-C4X-112956)
- Levofloxacin Impurity 03 (CAS 1213269-49-8)
- Brivudine impurity 7 (CAS CATO-C4X-27587)
- 3-Bromopyrazine-2-carboxamide (CAS 27825-22-5)
- 8-Amino-7-methylquinazolin-4(3H)-one (CAS 1093101-65-5)
- Methyl 3-(3-(4-fluorophenyl)thioureido)-4-methylthiophene-2-carboxylate (CAS 2197054-51-4)
- 3-[2-(Ethoxycarbonyl)-1-methyl-1H-indol-3-yl]propanoic acid (CAS 950275-71-5)
- 3-(4-Fluorophenoxy)-5-(trifluoromethyl)pyridine-2-carboxamide (CAS 338758-83-1)
- Encorafenib Impurity 11 (CAS CATO-C4X-32411)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com