N-[4-({3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-3-oxoprop-1-en-1-yl}amino)benzenesulfonyl]guanidine CAS 1211985-68-0
| CAS No. | 1211985-68-0 |
| Molecular Formula | C19H16ClN5O3S2 |
| Molecular Weight | 461.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-[4-({3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-3-oxoprop-1-en-1-yl}amino)benzenesulfonyl]guanidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-[4-({3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-3-oxoprop-1-en-1-yl}amino)benzenesulfonyl]guanidine (CAS 1211985-68-0), molecular formula C19H16ClN5O3S2 and molecular weight 461.95 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-[4-({3-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]-3-oxoprop-1-en-1-yl}amino)benzenesulfonyl]guanidine (C19H16ClN5O3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H16ClN5O3S2 |
| Molecular Weight | 461.95 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
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