Biotin EP Impurity A CAS 1163708-46-0
| CAS No. | 1163708-46-0 |
| Molecular Formula | C18H28N4O4S2 |
| Molecular Weight | 428.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Biotin EP Impurity A (CAS 1163708-46-0) is a certified pharmaceutical impurity reference standard with the molecular formula C18H28N4O4S2 and a molecular weight of 428.57 g/mol.
Based on its molecular formula C18H28N4O4S2, Biotin EP Impurity A contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 428.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Biotin EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H28N4O4S2 |
| Molecular Weight | 428.57 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Biotin Standards
- SLC-(+)-Biotin, 97% (CAS 1864003-57-5)
- Biotin impurity 01 (CAS 33607-60-2)
- Biotin-PEG3-CH2COOH (CAS 1189560-96-0)
- Biotin-PEG3-oxyamine (CAS 1786206-22-1)
- Biotin-PEG3-SH (CAS 1244028-52-1)
- Biotin-PEG4-OH (CAS 1217609-84-1)
- N-(Biotin)-N-bis(PEG1-alcohol) (CAS 2100306-75-8)
- Biotin-PEG3-Amine (CAS 359860-27-8)
Recommended Standards
- N',N'-Dibenzyl-N-(4-tert-butylphenyl)butanediamide (CAS 271775-69-0)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
- 6-(5-(2-(1-Ethylquinolin-4(1H)-ylidene)ethylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid (CAS 89695-36-3)
- 2-((13-(Tosyloxy)tridecyl)oxy)acetic acid (CAS 2817805-37-9)
- Opicapone impurity 24 (CAS CATO-C4X-240424)
- Dobutamine Impurity 7 (CAS 126521-63-9)
- Famotidine Impurity 47 (CAS CATO-C4X-139247)
- 2-Cyclopropyl-N-isopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide (CAS 1350711-47-5)
- [5-(4-Bromophenyl)-3-methylisoxazol-4-yl]carbamic acid 1-(2-chlorophenyl)ethyl ester (CAS 1228689-78-8)
- N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-guanidino-4-methoxyphenyl)acrylamide (CAS 1810048-29-3)
- Atorvastatin EP Impurity A HCl (CAS 433289-84-0(free base))
- 1-(2-Fluoroethyl)-N-(4-methoxybenzyl)-4-methyl-1H-pyrazol-5-amine hydrochloride (CAS 1856101-41-1)
- 6-Amino-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid (CAS 1260386-70-6)
- Peptide Impurity 12 (CAS CATO-CPTD788812)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com