Gemcitabine Impurity 20 CAS 116371-66-5
| CAS No. | 116371-66-5 |
| Molecular Formula | C9H13F2N3O10P2 |
| Molecular Weight | 423.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Gemcitabine Impurity 20.
Gemcitabine Impurity 20 (CAS 116371-66-5) is a high-purity analytical reference standard with the molecular formula C9H13F2N3O10P2 and a molecular weight of 423.16 g/mol.
Gemcitabine Impurity 20 (C9H13F2N3O10P2) contains a carbohydrate-derived structure, an amide group, a phosphate ester group, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Gemcitabine Impurity 20 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H13F2N3O10P2 |
| Molecular Weight | 423.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Gemcitabine Standards
- Gemcitabine Impurity 10 (CAS 122111-11-9)
- Gemcitabine Impurity 4 (CAS 134877-43-3)
- Gemcitabine monophosphate (disodium) (CAS 1638288-31-9)
- Gemcitabine Impurity 35 (CAS CATO-C4X-137235)
- Gemcitabine Impurity 16 (CAS 1173824-58-2)
- Gemcitabine Impurity 11 (CAS 143157-25-9)
- Gemcitabine Impurity 9 (CAS 143157-22-6)
- Gemcitabine Impurity 10 (CAS 1217452-91-9)
Recommended Standards
- 3-(3,5-Dichlorophenyl)-1-[(1Z)-{[(2,4-dichlorophenyl)methoxy]imino}methyl]thiourea (CAS 477852-48-5)
- 1,3-Dibromo-5-(2-ethylhexyl)-4H-thieno[3,4-c]pyrrole-4,6(5H)-dione (CAS 1231160-83-0)
- Moxifloxacin Impurity 38 (CAS 139693-52-0)
- 1,3-Dibromo-5-octyl-4H-thieno[3,4-c]pyrrole-4,6(5H)-dione (CAS 566939-58-0)
- Methanesulfonamide, 1,1,1-trifluoro-N-[(11bS)-8,9,10,11,12,13,14,15-octahydro-4-oxido-2,6-bis[4-(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl]- (CAS 2757287-57-1)
- 2-(2-Bromoethyl)aniline hydrobromide (CAS 511302-91-3)
- 3-(Trifluoromethyl)piperidin-3-ol (CAS 1052713-79-7)
- (2R,3S)-2-Methylmorpholine-3-carboxylic acid (CAS 1571212-69-5)
- N-(2-(1H-pyrrol-1-yl)-5-(trifluoromethyl)phenyl)-4-methylbenzenesulfonamide (CAS 866010-60-8)
- (3-Ethoxy-4-methoxybenzyl)(1-ethylpropyl)amine (CAS 418778-20-8)
- Gefitinib Impurity 44 (CAS 367-22-6)
- (s)-4-(1-Amino-2-hydroxyethyl)-2-((dimethylamino)methyl)phenol (CAS 1213551-65-5)
- 5-(Chloromethyl)-1-methyl-3-phenyl-1h-pyrazole (CAS 869901-14-4)
- Peptide 442 (CAS CATO-CPTD788442)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com