Adefovir Impurity 6 CAS 116384-54-4
| CAS No. | 116384-54-4 |
| Molecular Formula | C10H16N5O4P |
| Molecular Weight | 301.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Adefovir Impurity 6 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 301.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Adefovir Impurity 6 (CAS 116384-54-4) is a certified pharmaceutical impurity reference standard with the molecular formula C10H16N5O4P and a molecular weight of 301.24 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Adefovir Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H16N5O4P |
| Molecular Weight | 301.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 5 |
Related Adefovir Standards
- Adefovir Dipivoxil Impurity 41 (CAS 107021-27-2)
- Adefovir Dipivoxil Impurity 32 (CAS 374678-38-3)
- Adefovir Dipivoxil Impurity 35 (CAS 374678-39-4)
- Adefovir (CAS 106941-25-7)
- Adefovir Impurity 5 (CAS 116384-53-3)
- Adefovir Impurity 37 (CAS CATO-C4X-115237)
- Adefovir Impurity 21 (CAS CATO-C4X-115221)
- Adefovir Impurity 22 (CAS CATO-C4X-115222)
Recommended Standards
- Tenofovir Monomethyl Ester (CAS 1796539-83-7)
- 4-Nitrophenyl β-D-Galactofuranoside (CAS 100645-45-2)
- Tenofovir disoproxil Impurity 109 (CAS CATO-C4X-1076109)
- 1-(Carboxymethyl)-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011400-21-7)
- Emedastine EP Impurity C DiHCl (CAS 122423-32-9 (free base))
- Hydrocortisone EP Impurity L (CAS 641-77-0)
- Isoconazole nitrate EP Impurity C (CAS 22832-87-7)
- 3-(propan-2-yl)-3-azabicyclo[3.1.1]heptan-6-one (CAS 1240529-24-1)
- 3-Butyl-1-methyl-1H-imidazol-3-ium perchlorate (CAS 220956-35-4)
- Methyl (3S,5S)-5-allylmorpholine-3-carboxylate (CAS 635714-22-6)
- (2-Fluoro-6-(hydroxymethyl)phenyl)boronic acid (CAS 1246633-54-4)
- 5-((5-Chloro-1H-benzo[d]imidazol-2-yl)thio)-2-nitroaniline (CAS 89028-83-1)
- 2-(1-Tosyl-1H-pyrrol-3-yl)acetic acid (CAS 1017789-74-0)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
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