(2Z)-3-[2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]-2-(3-methoxyphenyl)prop-2-enenitrile CAS 1164540-00-4
| CAS No. | 1164540-00-4 |
| Molecular Formula | C24H18ClN3O |
| Molecular Weight | 399.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2Z)-3-[2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]-2-(3-methoxyphenyl)prop-2-enenitrile.
(2Z)-3-[2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]-2-(3-methoxyphenyl)prop-2-enenitrile (CAS 1164540-00-4), molecular formula C24H18ClN3O and molecular weight 399.87 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, (2Z)-3-[2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]-2-(3-methoxyphenyl)prop-2-enenitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 399.87 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2Z)-3-[2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]-2-(3-methoxyphenyl)prop-2-enenitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H18ClN3O |
| Molecular Weight | 399.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Z Standards
- (2Z)-3-[2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl]-2-(4-methoxyphenyl)prop-2-enenitrile (CAS 1164546-48-8)
- (2Z)-3-[2-(4-Chlorophenyl)-7-methylimidazo[1,2-a]pyridin-3-yl]-2-(3-methoxyphenyl)prop-2-enenitrile (CAS 478248-61-2)
- 4-(4-Chlorophenyl)-1-(3,4-dimethoxyphenethyl)-2-methyl-1H-pyrrole-3-carboxylic acid (CAS 881041-71-0)
- N-(3-(3-(4-Chlorophenyl)-6-oxopyridazin-1(6H)-yl)propyl)-2-(4-fluorophenyl)acetamide (CAS 1040669-12-2)
- (2-Chlorophenyl)(3-((3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)methanone (CAS 1705134-84-4)
- (E)-{[4-(4-chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene}amino cyclopropanecarboxylate (CAS 383147-87-3)
- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino N-(4-methylphenyl)carbamate (CAS 477872-48-3)
- [4-(3-Chlorophenyl)-1-piperazinyl][3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methanone (CAS 933202-27-8)
Recommended Standards
- Avanafil Impurity 78 (CAS 372117-76-5)
- N'-((5-(4-Chlorobenzyl)-6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylene)isonicotinohydrazide (CAS 31349-14-1)
- N-(3-Chloro-4-methoxyphenyl)-5-methyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574622-11-9)
- Methyl 2-amino-4-(2-chlorophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939894-13-0)
- 3-(2-Bromophenyl)oxirane-2-carboxylic acid (CAS 130089-22-4)
- 1-(1,3-Dimethyl-1H-pyrazol-5-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 956742-44-2)
- Thymol O-β-D-Glucuronide (CAS 7702-71-8)
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- (2S)-2-[[4-(4-bromophenyl)phenyl]sulfonylamino]-3-methylbutanoic acid (CAS 199850-67-4)
- 3-Bromo-4-cyclopropylphenol (CAS 1784977-63-4)
- 4-Bromo-2-(((3,5-dimethoxyphenyl)amino)methyl)phenol (CAS 1223885-07-1)
- 3-Cyclohexen-1-amine (CAS 2655-68-7)
- Cyclopropyl(4-fluorophenyl)methanamine (CAS 705-14-6)
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Why CATO?
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