Econazole Impurity 6 CAS 116865-83-9
| CAS No. | 116865-83-9 |
| Molecular Formula | C8H5Cl3O |
| Molecular Weight | 223.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Econazole Impurity 6 (CAS 116865-83-9), a pharmacopoeial impurity reference standard (molecular formula C8H5Cl3O, MW 223.48 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Econazole Impurity 6 (C8H5Cl3O) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Econazole Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl3O |
| Molecular Weight | 223.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
Related Econazole Standards
- Econazole Impurity 11 (CAS 4252-78-2)
- Econazole Impurity 5 (CAS 81547-71-9)
- Econazole impurity 17 (CAS 24155-44-0)
- Econazole impurity 18 (CAS 24155-45-1)
- Econazole impurity 20 (CAS CATO-C4X-132720)
- Econazole impurity 21 (CAS 293759-26-9)
- Econazole impurity 27 (CAS 27087-94-1)
- Econazole impurity 29 (CAS 24155-32-6)
Recommended Standards
- Revefenacin impurity 105 (CAS CATO-C4X-2031105)
- Imatinib Impurity N13 (CAS 36747-64-5)
- Empagliflozin Impurity 93 (CAS 19932-79-7)
- 5-Allyl-2,4,6-trichloropyrimidine (CAS 10182-68-0)
- Salmeterol EP Impurity A Formate Salt (CAS CATO-C4X-105019)
- Dalbavancin Impurity 57 (CAS CATO-C4X-160257)
- Doxylamine EP Impurity C HCI (CAS 1221-70-1（free base）)
- 2-[(2-Hydroxyethyl)amino]nicotinic acid (CAS 1220018-27-8)
- (2S,3S)-2-Amino-3-methylpentanedioic acid hydrochloride (CAS 910548-22-0)
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- 2-Chloro-11-methyldibenzo[b,f][1,4]thiazepine-8-carboxylic acid (CAS 897771-53-8)
- 3-Carbamoyl-1-methoxypyridin-1-ium perchlorate (CAS 54212-30-5)
- Neuropeptide Y (22-36) (CAS 119019-65-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com