Econazole Impurity 5 CAS 81547-71-9
| CAS No. | 81547-71-9 |
| Molecular Formula | C8H5Cl3O |
| Molecular Weight | 223.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Econazole Impurity 5 (CAS 81547-71-9), a pharmacopoeial impurity reference standard (molecular formula C8H5Cl3O, MW 223.48 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Econazole Impurity 5 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 223.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl3O |
| Molecular Weight | 223.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
Related Econazole Standards
- Econazole Impurity 11 (CAS 4252-78-2)
- Econazole Impurity 6 (CAS 116865-83-9)
- Econazole impurity 17 (CAS 24155-44-0)
- Econazole impurity 18 (CAS 24155-45-1)
- Econazole impurity 20 (CAS CATO-C4X-132720)
- Econazole impurity 21 (CAS 293759-26-9)
- Econazole impurity 27 (CAS 27087-94-1)
- Econazole impurity 29 (CAS 24155-32-6)
Recommended Standards
- Empagliflozin Impurity 93 (CAS 19932-79-7)
- Revefenacin impurity 105 (CAS CATO-C4X-2031105)
- 2,2-Dichloro-1-(4-chlorophenyl)ethanone 4711AE 5157-57-3 C8H5Cl3O (CAS 5157-57-3)
- Imatinib Impurity N13 (CAS 36747-64-5)
- N-Nitroso Relebactam Impurity 51 (CAS CATO-C4X-214451)
- Metronidazole Impurity 30 (CAS 13182-90-6)
- Thioctic acid Impurity 81 (CAS CATO-C4X-152681)
- 2-Chloro-3,6-dimethylquinoxaline (CAS 860502-83-6)
- 2-Amino-1-(2-methoxy-5-methylphenyl)propan-1-one (CAS 682324-12-5)
- 3-Methyl-6-vinylpyridazine (CAS 848774-92-5)
- (S)-1-(2-chloro-6-fluorophenyl)propan-1-amine hcl (CAS 1391435-53-2)
- (2S,3S)-3-Methyl-2-(4-methylphenylsulfonamido)pentanoic acid (CAS 34235-81-9)
- Ethyl 3-(piperidin-3-yl)propanoate (CAS 91017-00-4)
- Acetyl tetrapeptide-9(Dermican LS 9837) (CAS 928006-50-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com