N-(5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)-1-methyl-1H-pyrazole-3-carboxamide CAS 1169950-10-0
| CAS No. | 1169950-10-0 |
| Molecular Formula | C13H10FN5O2 |
| Molecular Weight | 287.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)-1-methyl-1H-pyrazole-3-carboxamide.
N-(5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)-1-methyl-1H-pyrazole-3-carboxamide (CAS 1169950-10-0), molecular formula C13H10FN5O2 and molecular weight 287.25 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)-1-methyl-1H-pyrazole-3-carboxamide (C13H10FN5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 287.25 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10FN5O2 |
| Molecular Weight | 287.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related N Standards
- 1-(2-Fluorophenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1160246-27-4)
- 3-(3-Fluorophenyl)-2-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1204298-41-8)
- 2-(2-(4-Fluorophenyl)-4-oxopyrazolo[1,5-a]pyrazin-5(4H)-yl)acetic acid (CAS 1338670-00-0)
- 2-((1-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino)acetic acid (CAS 89454-13-7)
- 6-(4-Fluorophenyl)-2-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazole (CAS 368841-71-8)
- 5-Ethyl-2-(4-fluorophenyl)-3-(hydroxymethyl)pyrazolo[1,5-a]pyrazin-4(5H)-one (CAS 1341007-82-6)
- 5-Ethyl-2-(3-fluorophenyl)-3-(hydroxymethyl)pyrazolo[1,5-a]pyrazin-4(5H)-one (CAS 1713590-42-1)
- (E)-2-((4-fluorophenyl)amino)-N'-(2-hydroxybenzylidene)acetohydrazide (CAS 298218-07-2)
Recommended Standards
- N-(3-Nitrophenyl)-2-oxooxazolidine-3-sulfonamide (CAS 116943-61-4)
- Capecitabine Impurity 44 (CAS CATO-C4X-102444)
- 5-[3-(3-Fluoro-4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1,2-dihydropyridin-2-one (CAS 1338681-21-2)
- Capecitabine Impurity 43 (CAS CATO-C4X-102443)
- tert-Butyl [(1S)-1-(hydrazinocarbonyl)-3-(methylthio)propyl]carbamate (CAS 49759-74-2)
- 5-Chloro-2-(difluoromethoxy)-3-(trifluoromethyl)pyridine (CAS 1214379-40-4)
- N-Isobutyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine-2-carboxamide (CAS 1422066-64-5)
- 5-Bromo-3-methylindole (CAS 10075-48-6)
- 3-(Diethylamino)-1-(3-nitrophenyl)propan-1-one (CAS 92033-80-2)
- (2,3,4,5,6-Pentachlorophenyl)methyl 4-(diethylamino)-3-fluorobenzoate (CAS 329701-56-6)
- 2-(2,2-Difluoroethyl)-3-methyl-4-(trifluoromethyl)-2h-pyrazolo[3,4-b]pyridin-6-ol (CAS 1018127-62-2)
- 8,8-Difluoro-1-azaspiro[4.5]Decane-2-carboxylic acid (CAS 2387594-62-7)
- 2-Amino-1-(3,5-difluorophenyl)ethanone hydrochloride (CAS 1187931-06-1)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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