Risperidone Impurity 20 CAS 1172297-96-9
| CAS No. | 1172297-96-9 |
| Molecular Formula | C12H13F2NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Risperidone Impurity 20 (CAS 1172297-96-9), a pharmacopoeial impurity reference standard (molecular formula C12H13F2NOHCl, MW 261.70 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Risperidone Impurity 20 (C12H13F2NOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13F2NO HCl |
| Molecular Weight | 261.70 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Risperidone Standards
- Risperidone Impurity 27 (CAS 1005191-81-0)
- Risperidone-d4 (CAS 1020719-76-9)
- Risperidone (CAS 106266-06-2)
- Methyl Risperidone (CAS 106266-08-4)
- Risperidone EP Impurity K (CAS 106266-09-5)
- Risperidone impurity 46 (CAS 106266-11-9)
- Risperidone Impurity 32 (CAS 108855-18-1)
- Risperidone EP Impurity D (CAS 1199589-74-6)
Recommended Standards
- Upadacitinib Impurity 97 (CAS CATO-C4X-240597)
- Tiotropium Bromide EP Impurity B (CAS 136310-64-0)
- Daclatasvir Impurity 17 (CAS CATO-C4X-184817)
- 2-((2-Chloro-3-methyl-6-nitrophenyl)amino)phenol (CAS 858854-70-3)
- 5-Chloro-N-(1-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)cyclohexyl)-2-fluorobenzamide (CAS 1396799-48-6)
- Progesterone EP Impurity M (17-alpha-Progesterone) (CAS 2000-66-0)
- Ethyl 2-(methylthio)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-4-carboxylate (CAS 944901-89-7)
- 1-((5-Bromofuran-2-yl)methyl)-1H-pyrrole-2-carboxylic acid (CAS 1539612-09-3)
- 4-Amino-6-dimethylamino-2-methylpyrimidine (CAS 18260-58-7)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com