Defluoro Levofloxacin（Levofloxacin EP Impurity D） CAS 117620-85-6
| CAS No. | 117620-85-6 |
| Molecular Formula | C18H21N3O4 |
| Molecular Weight | 343.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Defluoro Levofloxacin（Levofloxacin EP Impurity D） (CAS 117620-85-6) is a certified pharmaceutical impurity reference standard with the molecular formula C18H21N3O4 and a molecular weight of 343.38 g/mol.
Defluoro Levofloxacin（Levofloxacin EP Impurity D） (C18H21N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H21N3O4 |
| Molecular Weight | 343.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >80% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Defluoro Standards
- Defluoro Flumazenil Isothiocyanate (CAS 954107-48-3)
- Defluoro Levofloxacin-d3 (CAS 1329836-14-7)
- 4-Defluoro-4-(1H-1,2,4-triazol-1-yl) Fluconazole-d4 (CAS 1794817-03-0)
- Defluoro Linezolid-d3 (CAS 1795786-92-3)
- Defluoro Paroxetine (CAS 1322626-23-2)
- 4-Defluoro-2-fluoro Haloperidol-d4 (CAS 1795021-11-2)
- Defluoro-decarboxyl Ofloxacin (CAS 1346602-33-2)
- Defluoro Hydroxy AM-694 (CAS 335160-94-6)
Recommended Standards
- Levofloxacin Impurity 30 (CAS CATO-C4X-137130)
- Ofloxacin EP Impurity C (CAS 95848-94-5)
- Ciprofloxacin Impurity 28 (CAS CATO-C4X-136228)
- Cefpodoxime Sulfoxide Impurity 1 (CAS CATO-C4X-179371)
- Isavuconazole Impurity 44 (CAS CATO-C4X-123644)
- Empagliflozin Impurity 84 (CAS CATO-C4X-106584)
- Eltrombopag Impurity 39 (CAS 103966-66-1)
- Ethyl 4-chloro-5,6,7,8-tetrahydro-1,7-naphthyridine-2-carboxylate (CAS 1884203-23-9)
- (2S,4R)-N-Boc-4-methyl-pipecolinic acid (CAS 1821781-02-5)
- (R)-1-(2,3,6-Trifluorophenyl)ethan-1-ol (CAS 1932252-96-4)
- Sodium Fusidate EP Impurity H (CAS 16711-91-4)
- 4-(1,1,2,2-Tetrafluoroethoxy)aniline (CAS 713-62-2)
- 3-(4-Cyanophenyl)-5-methoxybenzonitrile (CAS 1445322-49-5)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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