Eltrombopag Impurity 39 CAS 103966-66-1
| CAS No. | 103966-66-1 |
| Molecular Formula | C7H6BrNO3 |
| Molecular Weight | 232.03 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Eltrombopag Impurity 39 (CAS 103966-66-1), a pharmacopoeial impurity reference standard (molecular formula C7H6BrNO3, MW 232.03 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, Eltrombopag Impurity 39 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 232.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6BrNO3 |
| Molecular Weight | 232.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 32 (CAS 98775-19-0)
- Eltrombopag Impurity 36 (CAS 33696-00-3)
- Eltrombopag Impurity 38 (CAS 500298-30-6)
- Eltrombopag Impurity 56 (CAS CATO-C4X-119856)
- Eltrombopag Impurity 83 (CAS CATO-C4X-119883)
- Eltrombopag Impurity 84 (CAS CATO-C4X-119884)
- Eltrombopag Impurity 85(E-Isomer) (CAS CATO-C4X-119885)
- Eltrombopag Impurity 9 (CAS CATO-C4X-11989)
Recommended Standards
- 2-Bromo-3-nitrobenzyl alcohol (CAS 90407-20-8)
- 3-(2,4-Dichloro-5-fluorophenyl)isoxazole (CAS 103318-73-6)
- 3-(2,4-Dichloro-5-fluorophenyl)-3-oxopropanenitrile (CAS 103318-74-7)
- Methyl 6-bromo-3-hydroxypyridine-2-carboxylate (CAS 321601-48-3)
- Loratadine Impurity 89 (CAS CATO-C4X-142689)
- Tadalafil Impurity 161 (CAS CATO-C4X-1087161)
- Axitinib Impurity 27 (CAS CATO-C4X-107127)
- 2-tert-Butyl 4-methyl 2-azabicyclo[2.2.2]octane-2,4-dicarboxylate (CAS 2031259-79-5)
- 3,5-Dichloro-2-methylpyridin-4-ol (CAS 1823944-64-4)
- 3-(2-Fluoro-4-nitrophenoxy)oxetane (CAS 1356114-72-1)
- [(2R)-2-NItrocyclopropyl]benzene (CAS 1864012-31-6)
- Apalutamide Impurity 78 (CAS CATO-C4X-274978)
- 4-(n-(2,2,2-Trifluoroethyl)sulfamoyl)benzoic acid (CAS 610259-76-2)
- Cholecystokinin Octapeptide (1-3) (desulfated) H-Asp-Tyr-Met-OH (CAS 121880-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com