Dexamethasone EP Impurity G CAS 1177-87-3
| CAS No. | 1177-87-3 |
| Molecular Formula | C24H31FO6 |
| Molecular Weight | 434.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dexamethasone EP Impurity G is closely related to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Dexamethasone EP Impurity G (CAS 1177-87-3) is a certified pharmaceutical impurity reference standard with the molecular formula C24H31FO6 and a molecular weight of 434.50 g/mol.
Dexamethasone EP Impurity G (C24H31FO6) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dexamethasone EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H31FO6 |
| Molecular Weight | 434.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone EP Impurity B Disodium Salt (CAS 7460-03-9)
- Dexamethasone Acetate EP Impurity C (CAS CATO-C4X-116540)
- Dexamethasone Acetate EP Impurity B (CAS CATO-C4X-116550)
- Dexamethasone Acetate EP Impurity E (CAS 1524-94-3)
- Dexamethasone Impurity 112 (CAS 134429-26-8)
- Dexamethasone Impurity 83 (CAS 1879-87-4)
- Dexamethasone 17-Propionate (CAS 15423-89-9)
- Dexamethasone 21-Propionate (CAS 3793-10-0)
Recommended Standards
- Halcinonide Impurity 11 (CAS CATO-C4X-279511)
- Triamcinolone Acetonide (CAS 76-25-5)
- Apremilast Impurity 100 (CAS CATO-C4X-1009100)
- Betamethasone 21-Acetate (CAS 987-24-6)
- Bumetanide Impurity 37 (CAS CATO-C4X-198637)
- Vilanterol Impurity 37 (CAS 452339-70-7)
- Biapenem impurity 35 (CAS 1080648-58-3)
- 2-Chloro-5-nitro-N-(4-pyridyl)benzamide (CAS 313516-66-4)
- 1-(4-Chloro-2-fluoropyridin-3-yl)ethanone (CAS 1393554-97-6)
- 4-Cyanocyclohex-3-enecarboxylic acid (CAS 42038-77-7)
- 7-Bromo-8-chlorochroman-4-one (CAS 1273598-25-6)
- 4-Chloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-5-((2-hydroxyethyl)(methyl)amino)pyridazin-3(2H)-one (CAS 338399-91-0)
- (3S,4S)-tert-Butyl 3-fluoro-4-methylpyrrolidine-1-carboxylate (CAS 1932413-17-6)
- Semaglutide impurity 70 (CAS CATO-C4X-222670)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com