Dexamethasone Acetate EP Impurity E CAS 1524-94-3
| CAS No. | 1524-94-3 |
| Molecular Formula | C24H33FO6 |
| Molecular Weight | 436.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 436.51 g/mol gives Dexamethasone Acetate EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Dexamethasone Acetate EP Impurity E (CAS 1524-94-3, C24H33FO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Dexamethasone Acetate EP Impurity E (C24H33FO6) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dexamethasone Acetate EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H33FO6 |
| Molecular Weight | 436.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone EP Impurity B Disodium Salt (CAS 7460-03-9)
- Dexamethasone Acetate EP Impurity C (CAS CATO-C4X-116540)
- Dexamethasone Acetate EP Impurity B (CAS CATO-C4X-116550)
- Dexamethasone EP Impurity G (CAS 1177-87-3)
- Dexamethasone Impurity 83 (CAS 1879-87-4)
- Dexamethasone Impurity 112 (CAS 134429-26-8)
- Dexamethasone 17-Propionate (CAS 15423-89-9)
- Dexamethasone 21-Propionate (CAS 3793-10-0)
Recommended Standards
- Alogliptin impurity 84 (CAS CATO-C4X-109984)
- Triamcinolone Acetonide EP Impurity E (CAS 1524-86-3)
- 5-(2-(Benzyloxy)phenyl)-N'-(2-methyl-3-phenylallylidene)-1H-pyrazole-3-carbohydrazide (CAS 634895-29-7)
- Ruxolitinib Impurity 24 (CAS CATO-C4X-205824)
- Ampicillin Impurity 89 (CAS CATO-C4X-144389)
- Zoledronic Acid Impurity 6 (CAS 17450-34-9)
- Phytomenadione/Vitamin K1 Impurity 87 (CAS CATO-C4X-220787)
- Azelnidipine Impurity 5 (CAS 103426-18-2)
- 3-amino-3-(pyridin-2-yl)propanoic acid dihydrochloride (CAS 1423028-99-2)
- (2E)-3-(Furan-2-yl)-N-(3-methylphenyl)prop-2-enamide (CAS 15341-96-5)
- (9H-fluoren-9-yl)methyl (S)-(4-(methylthio)-1-oxobutan-2-yl)carbamate (CAS 211929-83-8)
- 2-Amino-4,4-diphenyl-1H-imidazol-5(4H)-one (CAS 26975-70-2)
- 1-Isobutyl-3-methyl-1h-pyrazole (CAS 405548-40-5)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com