Dexamethasone Impurity 112 CAS 134429-26-8
| CAS No. | 134429-26-8 |
| Molecular Formula | C24H30O7 |
| Molecular Weight | 430.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Dexamethasone Impurity 112 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Dexamethasone Impurity 112 (CAS 134429-26-8, C24H30O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C24H30O7, Dexamethasone Impurity 112 contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 430.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C24H30O7 |
| Molecular Weight | 430.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
Related Dexamethasone Standards
- Dexamethasone EP Impurity B Disodium Salt (CAS 7460-03-9)
- Dexamethasone Acetate EP Impurity C (CAS CATO-C4X-116540)
- Dexamethasone Acetate EP Impurity B (CAS CATO-C4X-116550)
- Dexamethasone EP Impurity G (CAS 1177-87-3)
- Dexamethasone Acetate EP Impurity E (CAS 1524-94-3)
- Dexamethasone impurity 79 (CAS CATO-C4X-116579)
- Dexamethasone Impurity 83 (CAS 1879-87-4)
- Dexamethasone Acetate EP Impurity G (CAS 1597-78-0)
Recommended Standards
- Lansoprazole impurity 63 (CAS 763899-08-7)
- Desonide Impurity 16 (CAS CATO-C4X-130116)
- Risperidone EP Impurity B (CAS 132961-05-8)
- Eplerenone Impurity 24 (CAS CATO-C4X-163024)
- Paliperidone Impurity 81 (CAS 691007-07-5)
- Doxapram Impurity 38 (CAS CATO-C4X-197338)
- Abemaciclib Impurity 168 (CAS CATO-C4X-2937168)
- (4-(3-Methoxyphenyl)thiazol-2-yl)methanamine (CAS 643723-49-3)
- methyl 2-[(4-hydroxyphenyl)sulfanyl]acetate (CAS 30512-63-1)
- 5-(((2-Bromo-5-chlorobenzyl)amino)methyl)pyrrolidin-2-one (CAS 1495894-69-3)
- 5-(isocyanatomethyl)-1,2,3-trimethoxybenzene (CAS 351003-01-5)
- N-(2-cyanopropyl)-N-ethyl-2-(phenylthio)acetamide (CAS 1252452-53-1)
- 2-Fluoro-N-(3-fluorobenzyl)-5-methylaniline (CAS 1039824-92-4)
- Influenza PR8 Hemagglutinin Peptide (110-119) (H-6312.0005) (CAS 132031-50-6)
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