6-Chloro-7-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine CAS 1178583-40-8
| CAS No. | 1178583-40-8 |
| Molecular Formula | C8H8ClN5 |
| Molecular Weight | 209.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Chloro-7-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-Chloro-7-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine (CAS 1178583-40-8), a certified reference material (molecular formula C8H8ClN5, MW 209.64 g/mol) for analytical method development and quality control.
The molecular framework of 6-Chloro-7-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine (C8H8ClN5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Chloro-7-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClN5 |
| Molecular Weight | 209.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 3-Chloro-2-[(difluoromethyl)sulfanyl]aniline (CAS 1095555-96-6)
- 6-Chloro-8-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine (CAS 1178583-36-2)
- 2-Chloro-5-methyl-4-(1-methyl-1H-1,2,4-triazol-5-yl)pyrimidine (CAS 1203114-58-2)
- 2-chloro-6H,7H,8H-pyrrolo[2,1-h]purin-6-amine (CAS 1251001-74-7)
- 4-Chloro-N-(1-methyl-1H-pyrazol-4-yl)pyrimidin-2-amine (CAS 1462286-01-6)
- 4-Chloro-N-(1-methyl-1H-pyrazol-5-yl)pyrimidin-2-amine (CAS 1673546-74-1)
- 2-Chloro-n-cyclopropyl-9h-purin-6-amine (CAS 195252-69-8)
- 1-(5-Chloro-1H-benzimidazol-2-yl)guanidine (CAS 70590-32-8)
Recommended Standards
- 1-(6-Chloropyrimidin-4-yl)-3-methyl-1H-pyrazol-5-amine (CAS 1018473-22-7)
- 9-Allyl-6-chloro-9H-purin-2-amine (CAS 144364-01-2)
- 4-Chloroindole-3-acetic Acid (CAS 2519-61-1)
- Cabozantinib Impurity 25 (CAS 205448-31-3)
- 3,3-Difluoro-1-(2-hydroxyethyl)cyclobutane (CAS 1056467-54-9)
- 2-Methoxy-4,6-dimethylbenzonitrile (CAS 854854-61-8)
- 4-Ethyl-1-hydroxycyclohexane-1-carboxylic acid (CAS 1249152-87-1)
- 4-Chloro-5-cyanopyridine-2-carboxylic acid (CAS 1256824-14-2)
- 2-Chloro-N-(4-ethynylphenyl)acetamide (CAS 1233382-40-5)
- 1,4,8-Triazaspiro[4.5]decan-2-one (CAS 1849207-14-2)
- Tert-butyl 2-(6-chloro-4-methylpyridin-3-yl)pyrrolidine-1-carboxylate (CAS 1352531-03-3)
- 2-(3-Aminopyridin-4-yl)acetonitrile (CAS 1227512-30-2)
- 1-({4-chloro-5-phenylthieno[2,3-d]pyrimidin-2-yl}methyl)piperidine (CAS 731815-64-8)
- Vialox Peptide(Pentapeptide-3) (CAS 135679-88-8)
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