Bumetanide Impurity 14 CAS 118-97-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.118-97-8
Molecular FormulaC7H3ClN2O6
Molecular Weight246.56 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bumetanide Impurity 14 CAS 118-97-8 chemical structure

Description

The occurrence of Bumetanide Impurity 14 is closely related to a carbohydrate-derived structure, an amide group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Bumetanide Impurity 14 (CAS 118-97-8), a pharmacopoeial impurity reference standard (molecular formula C7H3ClN2O6, MW 246.56 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C7H3ClN2O6, Bumetanide Impurity 14 contains a carbohydrate-derived structure, an amide group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 246.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H3ClN2O6
Molecular Weight246.56 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentCl-containing
Nitrogen Atoms2

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