N4-Benzoyl-2’-O-tert-butyldimethylsilyl-5’-O-DMT-cytidine 3’-CE phosphoramidite CAS 118380-84-0

Purity 97%+In StockPharmaceutical Standards
CAS No.118380-84-0
Molecular FormulaC52H66N5O9PSi
Molecular Weight964.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N4-Benzoyl-2’-O-tert-butyldimethylsilyl-5’-O-DMT-cytidine 3’-CE phosphoramidite CAS 118380-84-0 chemical structure

Description

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, N4-Benzoyl-2’-O-tert-butyldimethylsilyl-5’-O-DMT-cytidine 3’-CE phosphoramidite is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 964.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

N4-Benzoyl-2’-O-tert-butyldimethylsilyl-5’-O-DMT-cytidine 3’-CE phosphoramidite (CAS 118380-84-0) is a high-purity analytical reference standard with the molecular formula C52H66N5O9PSi and a molecular weight of 964.17 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC52H66N5O9PSi
Molecular Weight964.17 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)22.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Nitrogen Atoms5

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