Clozapine-d8 CAS 1185053-50-2
| CAS No. | 1185053-50-2 |
| Molecular Formula | - |
| Molecular Weight | 334.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Clozapine-d8 (C18H11D8ClN4) contains deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Clozapine-d8 (CAS 1185053-50-2), molecular formula C18H11D8ClN4 and molecular weight 334.87 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Clozapine-d8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H11D8ClN4 |
| Molecular Weight | 334.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Clozapine Standards
- Clozapine-D4 (CAS 204395-52-8)
- Clozapine-D3 (CAS 1215691-72-7)
- Clozapine Impurity 22 (CAS CATO-C4X-134022)
- Clozapine N-Oxide (CAS 34233-69-7)
- Clozapine (CAS 5786-21-0)
- Clozapine EP Impurity D (CAS 65514-71-8)
- Clozapine Impurity 20 (CAS CATO-C4X-134020)
- Clozapine EP Impuirty C-D8 N-nitroso (CAS CATO-C4X-134018)
Recommended Standards
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- N,N-Dimethyl-3-methoxy-4-nitrosoaniline (CAS 7474-80-8)
- 7-Chlorofuro[3,2-b]pyridine-2-carbonitrile (CAS 220992-47-2)
- Fibronectin Fragment (1377-1388) (H-2572.0001) (CAS 162257-99-0)
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- 4-Amino-2-methyl-2,3-dihydrobenzofuran-7-carboxylic acid (CAS 166743-19-7)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com