Terbinafine Impurity 31 CAS CATO-C4X-133831
| CAS No. | CATO-C4X-133831 |
| Molecular Formula | C17H17Cl2N |
| Molecular Weight | 306.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Terbinafine Impurity 31 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Terbinafine Impurity 31 (CAS CATO-C4X-133831, C17H17Cl2N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Terbinafine Impurity 31 (C17H17Cl2N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Terbinafine Impurity 31 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17Cl2N |
| Molecular Weight | 306.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Terbinafine Standards
- Terbinafine impurity 34 (CAS CATO-C4X-133834)
- Terbinafine EP Impurity D (CAS 151222-50-3)
- Terbinafine Impurity N2 (CAS 99473-15-1)
- Terbinafine Impurity 48 (CAS CATO-C4X-133848)
- Terbinafine Impurity 49 (CAS CATO-C4X-133849)
- Terbinafine Impurity 1 (CAS 134274-69-4)
- Terbinafine Impurity 5-d7 (CAS 1185238-58-7)
- Terbinafine lmpurity 36 (CAS CATO-C4X-133836)
Recommended Standards
- Blonanserin Impurity 23 (CAS CATO-C4X-111023)
- Sertraline Impurity 53 (CAS 2184053-08-3)
- 3475-74-9 N-(4-Dimethylamino-3,5-dinitrophenyl)maleimide 1-(4-(Dimethylamino)-3,5-dinitrophenyl)-1H-pyrrole-2,5-dione Maleimide, N-(4-(dimethylamino)-3,5-dinitrophenyl)- 1H-Pyrrole-2,5-dione, 1-(4-(dimethylamino)-3,5-dinitrophenyl)- 4-21-00-04641 (Beilstein Handbook Reference) AI3-62630 BRN 0333082 N-(4-Dimethylamino-3,5-dinitrophenyl)-maleimide EINECS 222-449-3 NSC 90450 (CAS 3475-74-9)
- Sertraline (CAS 79617-96-2)
- Clonazepam EP Impurity B (CAS 55198-89-5)
- Clozapine Impurity 14 (CAS 1025951-76-1)
- Edaravone impurity 37 (CAS CATO-C4X-106237)
- 7-(1-(3,5-Dimethylphenoxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 306979-70-4)
- Ziprasidone impurity 49 (CAS CATO-C4X-124049)
- 5-Fluorobenzo[d]isoxazol-3-amine hydrochloride (CAS 916571-99-8)
- 2-(3,4-Dichlorophenyl)-N-methylpent-4-en-1-amine (CAS 206997-68-4)
- 4-Bromo-N-isopropylbenzenesulfonamide (CAS 1984-27-6)
- 4-Bromo-6-methylpyridine-2-methanol (CAS 448906-60-3)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
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