Agomelatine Impurity 4 CAS CATO-C4X-11084
| CAS No. | CATO-C4X-11084 |
| Molecular Formula | C26H25NO3 |
| Molecular Weight | 399.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Agomelatine Impurity 4 (CAS CATO-C4X-11084), a pharmacopoeial impurity reference standard (molecular formula C26H25NO3, MW 399.48 g/mol) used for the identification and quantification of trace impurities in APIs.
Agomelatine Impurity 4 (C26H25NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H25NO3 |
| Molecular Weight | 399.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Agomelatine Standards
- Agomelatine Impurity 9 (CAS CATO-C4X-11089)
- Agomelatine Impurity 3 (CAS 1385018-57-4)
- Agomelatine impurity 31 (CAS CATO-C4X-110831)
- Agomelatine Impurity 1 (CAS 1385018-58-5)
- Agomelatine Impurity 2 (CAS 185421-27-6)
- Agomelatine Diacetyl Impurity (CAS 1379005-34-1)
- Agomelatine Impurity 53 (CAS CATO-C4X-110853)
- Agomelatine Impurity 28 (CAS CATO-C4X-110828)
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- Rosuvastatin Impurity 190 (CAS CATO-C4X-1169190)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com