Baricitinib Impurity N1 CAS 1187595-88-5
| CAS No. | 1187595-88-5 |
| Molecular Formula | C19H29N5O2Si |
| Molecular Weight | 387.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Baricitinib Impurity N1 (CAS 1187595-88-5), a pharmacopoeial impurity reference standard (molecular formula C19H29N5O2Si, MW 387.55 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Baricitinib Impurity N1 (C19H29N5O2Si) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Baricitinib Impurity N1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H29N5O2Si |
| Molecular Weight | 387.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 5 |
Related Baricitinib Standards
- Baricitinib Impurity 63 (CAS CATO-C4X-226063)
- Baricitinib Impurity N5 (CAS 1153949-15-5)
- Baricitinib Impurity 103 (CAS CATO-C4X-2260103)
- Baricitinib Impurity 6 (CAS 2271228-51-2)
- Baricitinib Impurity 64 (CAS 1187594-34-8)
- Baricitinib Impurity 66 (CAS 1187594-33-7)
- Baricitinib Impurity 114 (CAS CATO-C4X-2260114)
- Baricitinib Impurity 49 (CAS CATO-C4X-226049)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com