Baricitinib Impurity 114 CAS CATO-C4X-2260114
| CAS No. | CATO-C4X-2260114 |
| Molecular Formula | C16H18N6O4S |
| Molecular Weight | 390.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Baricitinib Impurity 114 (CAS CATO-C4X-2260114, C16H18N6O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H18N6O4S, Baricitinib Impurity 114 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 390.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18N6O4S |
| Molecular Weight | 390.42 g/mol |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Baricitinib Standards
- Baricitinib Impurity 49 (CAS CATO-C4X-226049)
- Baricitinib Impurity 5 (CAS 2271228-52-3)
- Baricitinib Impurity 52 (CAS 2910813-43-1)
- Baricitinib Impurity 1 (CAS 2964606-42-4)
- Baricitinib Impurity 103 (CAS CATO-C4X-2260103)
- Baricitinib Impurity 6 (CAS 2271228-51-2)
- Baricitinib Impurity N5 (CAS 1153949-15-5)
- Baricitinib Impurity N1 (CAS 1187595-88-5)
Recommended Standards
- 4-[2-Nitro-4-(trifluoromethyl)phenyl]-N-propyl-1,4-diazepane-1-carbothioamide (CAS 900019-59-2)
- 2-Phenyl-N-(2-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)ethyl)acetamide (CAS 896375-40-9)
- 1,4-Bis(2-fluoro-4-isopropoxyphenyl)butane-1,4-dione (CAS 289039-80-1)
- 5,6-Dinitro-4,7-di(thiophen-2-yl)benzo[c][1,2,5]thiadiazole (CAS 165190-73-8)
- Regorafenib Impurity 71 (CAS CATO-C4X-104771)
- Avibactam Impurity 41 (CAS CATO-C4X-134841)
- Apixaban Impurity 79 (CAS 2435783-75-6)
- methyl 2-(((benzyloxy)carbonyl)amino)-3-(tosyloxy)propanoate (CAS 21142-81-4)
- 3-Ethyldihydrofuran-2(3H)-one (CAS 13888-01-2)
- 4-Ethyl-5-(5-propylthiophen-3-yl)-4H-1,2,4-triazole-3-thiol (CAS 438230-64-9)
- 6-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyridine (CAS 2435579-38-5)
- Homsi(r) p-(4-methylpiperazine)phenyl (CAS 1244855-66-0)
- N-(tert-Butyl)-2-(dimethylamino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-sulfonamide (CAS 1416336-57-6)
- RGD-targeted Proapoptotic Peptide trifluoroacetate salt (CAS 2243207-09-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com