Pitavastatin Impurity 51 CAS 1187966-93-3
| CAS No. | 1187966-93-3 |
| Molecular Formula | C25H21FNNaO4 |
| Molecular Weight | 441.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Pitavastatin Impurity 51 (CAS 1187966-93-3), a pharmacopoeial impurity reference standard (molecular formula C25H21FNNaO4, MW 441.43 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Pitavastatin Impurity 51 (C25H21FNNaO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H21FNNaO4 |
| Molecular Weight | 441.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Pitavastatin Standards
- Pitavastatin Impurity 116 (CAS CATO-C4X-1037116)
- Pitavastatin Impurity 50 (CAS 1980814-87-6)
- Pitavastatin Impurity 87 (CAS 224320-09-6)
- Pitavastatin Impurity 135 (CAS CATO-C4X-1037135)
- Pitavastatin Impurity 16 (CAS 849811-78-5)
- Pitavastatin Impurity 106 (CAS CATO-C4X-1037106)
- Pitavastatin 3-Oxo Ethyl Ester (CAS 148901-69-3)
- Pitavastatin Impurity 109 (CAS CATO-C4X-1037109)
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- 2-(P-tolyl)-1H-benzo[d]imidazol-1-ol (CAS 59276-97-0)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
Why CATO?
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